Drug interactions Flashcards

1
Q

Wha are common enzyme inducers?

A
CRAPS
Carbamazepine
Rifampacin
Alcohol (chronic)
Phenytoin 
St John's wort
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2
Q

What are common enzyme inhibitors?

A
A OK (d)EVICES 
Allopurinol
Omeprazole
Ketoconazole
Erythromycin 
Valproate 
Isoniazid 
Ciprofloxacin 
Ethanol
SSRIs
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3
Q

What drugs interact with statins?

A

Clarithromycin, erythromycin
Warfarin
Clopidogrel (simvastatin)
Amlodipine

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4
Q

What drugs interact with clopidogrel?

A

Simvastatin

Omeprazole

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5
Q

What drugs commonly interact with warfarin?

A

Enzyme inducers (CRAPS) and inhibitors (A OK dEVICES)
NSAIDs
Paracetamol
Statins

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6
Q

What drugs commonly interact with lithium?

A

NSAIDs

Diuretics

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7
Q

What drugs commonly interact with diuretics?

A

Lithium
NSAIDs
ACEi (with K sparing)

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8
Q

What drugs commonly interact with NSAIDs?

A

Lithium
Diuretics
SSRIs
Warfarin

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9
Q

What drug should never be prescribed with BB?

A

Verapamil

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10
Q

What drug should be avoided with ACEi?

A

K sparing diuretics eg spironolactone

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11
Q

What does amlodipine interact with?

A

Simvastatin

Decrease simvastatin dose

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