Common drugs Flashcards

1
Q

What are the common side effects of ACEi?

A

Bradykinin cough

Hyeprkalaemia

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2
Q

When should ACEi be stopped pre op?

A

Withhold morning of

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3
Q

What is the indication for amiodarone?

A

Tachyarrythmias

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4
Q

What is the acute care dose of amiodarone?

A

300mg

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5
Q

What are the contraindications for amiodarone?

A

Severe hypotension
Heart block
Active thyroid disease

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6
Q

What are beta lactic antibiotics?

A

Penicillins

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7
Q

What combination antibiotics contain penicillin?

A

Co-amoxiclav

Tazocin

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8
Q

What are sulphonamide antibiotics?

A

Trimethoprim

Co-trimazole

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9
Q

What are the contraindications for tetracycline antibiotics?

A

Children

Pregnant, breastfeeding

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10
Q

What side effects should be noted in tetracyclines?

A

GI upset common

Photosensitivity

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11
Q

What are macrolide antibiotics?

A

Azithromycin
Clarithromycin
Erythromycin

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12
Q

What should be remembered about clarithromycin and erythromycin?

A

Interact with statins- stop statins when on

Erythromycin= enzyme inhibitor- be wary with warfarin

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13
Q

What is an amino glycoside antibiotic?

A

Gent

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14
Q

What are the important adverse effects of gent?

A

Oto and renal toxicity

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15
Q

What are the important adverse effects of vanc?

A

Nephrotoxicity

Thrombophlebitis

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16
Q

When should caution be used with vanc and gent?

A

Renal impairment

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17
Q

What antibiotics cause C diff?

A

Co-amoxiclav
Clindamycin
Cephalosporins
Ciprofloxacin

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18
Q

What are the common types of anticoagulant?

A

LMWH
Unfractioned heparin
Warfarin
DOAC

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19
Q

When should anticoagulants be stopped pre op?

A

7 days

5 days in warfarin

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20
Q

What are common firstline anti-emetics?

A

Cyclizine 50mg
Metoclopramide 10mg
Ondansetron 4mg

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21
Q

When is metoclopramide especially useful?

A

Heart failure

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22
Q

When is metoclopramide contraindicated?

A

Bowel obstruction

Parkinson’s

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23
Q

When is ondansetron useful?

A

Chemo

GA

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24
Q

When is ondansetron contraindicated?

A

Long QT

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25
What are some common antiepeleptics?
``` Valproate Carbamazepine Phenytoin Lamotrigine Levetiracetam ```
26
What must be remembers about many antiepeleptics?
Enzyme interactions Indicer= carbamazepine, phenytoin Inhibitor= valproate
27
What is the side effect of note in carbamazepine?
Agranulocytosis
28
What are contraindications to benzos?
REsp depression | Liver failure
29
What are contraindications for BB?
Asthma Heart block Rate limiting CCB
30
Wha are types of rate limiting CCB?
CErapamil | Diltiazem
31
What are contraindications for rate limiting CCB?
``` BB Heart failure (w reduced ejection fraction) ```
32
What are vasodilating CCBs?
Amlodipine (5-10mg) | Felodipine, nifedipine
33
What are common side effects od vasodilating CCBS?
Oedema | Headache
34
When do steroids have to be tapered?
>3 weeks | 40mg for >7 days
35
What is the most to least potent corticosteroid?
Dexamethasone Prednisolone Hydrocortisone
36
What are common side effects of steroids?
``` Hyperglycaemia Cushing's syndrome Muscle wasting Osteoporosis Peptic ulcers Psych ```
37
What are features of digoxin toxicity?
N&V, blurred vision | bradycardia- can be tachy
38
What are contraindications for digoxin?
HEart block | Ventricular arrythmia
39
What should be monitored with digoxin?
ECG U&Es Less commonly dig level
40
What is important to remember with digoxin?
Can be digitoxic in normal range | Microgram dose
41
What are types of diuretics?
Loop diuretics K sparing Thiazide type
42
What are loop diuretics?
Firosemide | Bumetanide
43
What are side effects of loop diuretics?
Hypokalaemia | Hyponatraemia
44
What is a K sparing diuretic?
Spironolactone
45
What are contraindications for K sparing diuretic?
ACEi Renal impairment Hyperkalaemia
46
What should be remembered with K sparing diuretics?
Withhold morning of surgery | Can cause hyperkalaemia
47
What are TTDs?
Bendroflumethiazide, indapamide
48
What are side effects of TTDs?
Hypokalaemia | Hyponatraemia
49
What are the side effects of metformin?
GI upset | Lactic acidosis
50
What are the contraindications for metformin?
AKI Severe renal impairment 48 hours before and after contrast
51
What are the side effects of gliclazide?
Hypoglycaemia | Weight gain
52
What are the contraindications for laxatives?
Obstruction
53
What are the types of laxative?
Osmotic | Stimulant
54
What is an osmotic laxative?
Lactulose
55
What are stimulant laxatives?
Senna Docusate Glycerol suppositories
56
What is the usual dose of lidocaine?
1% solution | 200mg (3mg/kg)
57
What is the max dose of lidocaine with adrenaline?
500mg (7mg/kg)
58
What is the amount od adrenaline in lidocaine and adrenaline?
1:200,000 (5 micrograms/ml)
59
What is the dose of naloxone?
400-1200micrograms | Small increments
60
What are short and long acting nitrates?
GTN | Isosorbide mononitrate
61
What is essential with nitrates?
Nitrate free period daily
62
What are the side effects of nitrates?
Flushing | Hypotension
63
What are the contraindications of nitrates?
Severe aortic stenosis | Hypotension
64
What are the adverse effects of NSAIDs?
Renal impairment | Peptic ulcers
65
What are the contraindications to NSAIDs?
``` Heart failure Renal failure CABG Asthma Ulcers 3rd trimester ```
66
What are PPIs?
Omeprazole 10-20mg | Lansoprazole 15-30mg
67
What is a risk with long term PPI use?
Osteoporosis
68
What are the side effects f statins?
Myalgia | Rhabdomyolysis
69
What drugs do statins interact with?
Clarithromycin, erythromycin Clopidogrel Amlodipine Warfarin
70
What are contraindications for statins?
Hepatic impairment