Drug interactions Flashcards

1
Q

Two drugs that cause Type 1 allergic reactions

A

Penicllins, contrast media

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2
Q

Three drug classes that cause Type II allergic reactions

A

Penicillins, cephalosporins, oral hypoglycaemics

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3
Q

Two drug classes that cause type 3 allergic reactions

A

Penicillins, sulphonamides

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4
Q

Two drug classes that cause type IV allergic reaction

A

Topical antibiotics, antihistamine creams

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5
Q

ADRs: What rash or rashes can penicillin cause?

  1. Urticaria
  2. Erythema multiforme
  3. Photosensitivity
  4. Fixed eruptions
  5. Lupus-like reactions
A

Urticaria, erythema multiforme, lupus like reactions.

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6
Q

ADRs: What rash or rashes can Contrast media cause?

  1. Urticaria
  2. Erythema multiforme
  3. Photosensitivity
  4. Fixed eruptions
  5. Lupus-like reactions
A

Urticaria

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7
Q

ADRs: What rash or rashes can sulphonamides cause?

  1. Urticaria
  2. Erythema multiforme
  3. Photosensitivity
  4. Fixed eruptions
  5. Lupus-like reactions
A

Erythema multiforme, erythema nodosum, fixed eruptions, photosensitivity

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8
Q

ADRs: What rash or rashes can the OCP cause?

  1. Urticaria
  2. Erythema multiforme
  3. Photosensitivity
  4. Fixed eruptions
  5. Lupus-like reactions
A

Erythema nodosum

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9
Q

ADRs: What rash or rashes can Amiodarone cause?

  1. Urticaria
  2. Erythema multiforme
  3. Photosensitivity
  4. Fixed eruptions
  5. Lupus-like reactions
A

Photosensitivity

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10
Q

ADRs: What rash or rashes can Thaizides cause?

  1. Urticaria
  2. Erythema multiforme
  3. Photosensitivity
  4. Fixed eruptions
  5. Lupus-like reactions
A

Photosensitivity

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11
Q

ADRs: What rash or rashes can Erythromycin cause?

  1. Urticaria
  2. Erythema multiforme
  3. Photosensitivity
  4. Fixed eruptions
  5. Lupus-like reactions
A

Fixed eruptions

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12
Q

ADRs: What rash or rashes can Isonazid cause?

  1. Urticaria
  2. Erythema multiforme
  3. Photosensitivity
  4. Fixed eruptions
  5. Lupus-like reactions
A

Lupus-like reactions

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13
Q

ADRs: What rash or rashes can Hydralazine cause?

  1. Urticaria
  2. Erythema multiforme
  3. Photosensitivity
  4. Fixed eruptions
  5. Lupus-like reactions
A

Lupus-like reactions

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14
Q

ADRs: Drugs that cause intrahepatic cholestasis

List 7

A
Pills That Cause Cholestasis AS a SE
Phenothiazines
Tryclics
Clavulanic acid
Carbimazole
Anabolic steroids 
Sulfonyureas
Erythromycin
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15
Q

ADRs: Drugs that cause hepatocellular damage

List 7

A
Tricyclics (also intrahepatic cholestasis)
Anti-TB:
- Isonazid
- Pyrazinamide
Paracetamol
Methotrexate
Methyldopa
Phenytoin
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16
Q

ADRs: drugs that cause chronic hepatitis (list 2)

A

Methyldopa

Isonazid

17
Q

ADRs: drug classes that cause gallstones (list 2)

A

Fibrates

Oestrogens

18
Q

ADRs: drugs that cause pancytopenia (list 5)

A
Cytotoxics,
Chloramphenicol, 
Pheytoin, 
Penicillamines, 
Phenothiazides
19
Q

ADRs: drugs that cause Neutropenia (List 4)

A

The three C’s and Sulfonazide
Carbimasole
Barbamezapin
Clozapine

20
Q

ADRs: drugs that cause thrombocytopenia (list 5)

A
Sodum valporate
Chloroquinine
Catopril
Quin(id)ine
Salicylates
21
Q

ADRs: drugs tat cause peripheral neuropathy

A
Amiodarone
Nitrofuratoin
Vincristine
Cis-platin
Penicillamine
22
Q

Drugs causing pulmonary fibrosis

A

Amiodarone
Bleomycin
Busulfan

23
Q

Inhibitors of Cyto P450

A
SICKFACE.COM
Sodium valporate
Isonazid
Cimetidine
Ketoconazole
Fluconazole
Alcohol
Chloramphenicol
Erythromycin
Ciprofloxacin
Omeprazole
Metronidazole

Grafe fruit juice.

24
Q

Induction of city P450

A
Phenytoin
Phenoarbitone
Carbamezapine
Rifampacin
St. John's Wort