Drug Interactions

Question 1

Synergistic Effect

Answer 1

Two drugs enhance each other’s effects (e.g., aspirin + warfarin = increased bleeding risk)

Question 2

Antagonistic Effect

Answer 2

One drug blocks another (e.g., naloxone blocks opioids)

Question 3

Enzyme Induction

Answer 3

(e.g., rifampin increases breakdown of oral contraceptives making them less effective)

Question 4

Enzyme Inhibition

Answer 4

(e.g., grapefruit juice inhibits CYP450 enzymes increasing drug levels)

Question 5

Grapefruit Juice

Answer 5

Increases drug toxicity (affects statins, calcium channel blockers)

Question 6

Tyramine (found in aged cheese, wine)

Answer 6

can cause hypertension crisis when taken with MAOIs (e.g., phenelzine)

Question 7

Vitamin K (found in leafy greens)

Answer 7

can reduce the effects of warfarin (blood thinner)

Question 8

Beta-Blockers & Asthma

Answer 8

Beta-Blockers (e.g., propranolol) can worsen asthma by constricting airways

Question 9

NSAIDs & Kidney Disease

Answer 9

NSAIDs (e.g., ibuprofen) can worsen kidney function