drug interactions

Question 1

when does a drug interaction occur?

Answer 1

A drug interaction occurs when a substance alters the expected performance of a drug

Question 2

define a pharmacodynamic drug reaction.

Answer 2

occurs when drugs have an effect on the same target or physiological system

Question 3

define a pharmacokinetic drug reaction.

Answer 3

occurs when a drug affects the pharmacokinetics (absorption, distribution, metabolism or excretion) of another drug

Question 4

outline and explain the interactions of a pharmacodynamic drug reaction.

Answer 4

Pharmacodynamic interactions are either synergistic or antagonistic
Due to drugs acting on the same drug receptor(s) or physiological system
Generally predictable (related to pharmacology of drug)
Highly selective drugs are less likely to be problematic