Drug Interactions

Question 1

Drug- Drug Interactions

Answer 1

Possible toxicity
Ineffectiveness
Increased side effects
Ex: Ace Inhibitors & Spironalctone = Hyperkalemia (high potassium blood levels)

Question 2

Drug- Dietary Supplements

Answer 2

Antidepressants & St. John’s Warts = too much serotonin (serotonin syndrome)
High blood pressure, headache,seizure

Benzos & Kava kava = sleepy

Question 3

Drug- Nutrients

Answer 3

Vitamins and minerals in food
Tetracyclines & Ca rich foods = lower levels of

Question 4

Drug-food interactions

Answer 4

MAOI’s- fermented food drinks and cured meats; (phenelzine) & tyramine = high blood pressure

HMG-CoA reductase + grapefruit = increased statin levels (cholesterol)

Question 5

Drug - disease interactions

Answer 5

Beta-blockers =worsen asthma

Nasal congestants = high blood pressure

Question 6

Drugs-laboratory interactions

Answer 6

Pharmacological change results of lab tests
Common with urine