Drug interactions Flashcards

1
Q

List common CYP inhibitors

A

G PACMAN

Grapefruit
Protase inhibitors (ritonivir)
Azole antifungals
Cyclosporine
Macrolides
Amiodarone
Non-DHP CCBs

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2
Q

List common CYP inducers

A

PS PORCS

Phenytoin
Smoking
Phenobarbital
Oxcarbazepine
Rifampin
Carbamazepine
St. John’s wort

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3
Q

CYP2D6 inhibitors

A

PAFF
Paroxetine
Amiodarone
Fluoxetine
Fluvoxamine

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4
Q

What drugs cause ototoxicity?

A

Some Agents Can Lower Volume

Salicylates
Aminoglycosides
Cisplatin
Loop diuretics
Vancomycin

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5
Q

What drugs cause nephrotoxicity?

A

Always Check Culprits that Lower Normal Renal function

Anti-infectives (aminoglycosides, amphotericin, polymixin, vancomycin)
Cisplatin
Calcineurin inhibitors
Loop diuretics
NSAIDs
Radigraphic-contrast dye

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