Drug interactions Flashcards
1
Q
List common CYP inhibitors
A
G PACMAN
Grapefruit
Protase inhibitors (ritonivir)
Azole antifungals
Cyclosporine
Macrolides
Amiodarone
Non-DHP CCBs
2
Q
List common CYP inducers
A
PS PORCS
Phenytoin
Smoking
Phenobarbital
Oxcarbazepine
Rifampin
Carbamazepine
St. John’s wort
3
Q
CYP2D6 inhibitors
A
PAFF
Paroxetine
Amiodarone
Fluoxetine
Fluvoxamine
4
Q
What drugs cause ototoxicity?
A
Some Agents Can Lower Volume
Salicylates
Aminoglycosides
Cisplatin
Loop diuretics
Vancomycin
5
Q
What drugs cause nephrotoxicity?
A
Always Check Culprits that Lower Normal Renal function
Anti-infectives (aminoglycosides, amphotericin, polymixin, vancomycin)
Cisplatin
Calcineurin inhibitors
Loop diuretics
NSAIDs
Radigraphic-contrast dye