Drug information

Question 1

Drug identification and availability (3 points)

Answer 1

Mediview
HSA
MIMS

Question 2

Pregnancy (4 points)

Answer 2

Briggs (Drugs in Pregnancy and Lactation)
Micromedex
US CDC Treating for two guidelines
Uptodate Lexicomp

Question 3

Lactation (5 points)

Answer 3

Hales
Lactmed
Briggs (Drugs in Pregnancy and Lactation)
Micromedex
Uptodate lexicomp

Question 4

Choice of therapy (2 points)

Answer 4

ACE guidelines
MOH guidelines

Question 5

Dosing (3 points)

Answer 5

Uptodate lexicomp
Micromedex
BNF

Question 6

Parenteral administration (4 points)

Answer 6

PIL

Trissels (AHFS Handbook on injectable drugs)

(only for fluid restricted patients) Pediatric Injectable Drugs: The Teddy Bear Book

Uptodate Lexicomp

Question 7

Parenteral compatability (4 points)

Answer 7

Trissels (AHFS Handbook on injectable drugs)
Tissels 2.0
King’s Guide
Uptodate Lexicomp

(limited info cos manufacturers don’t do compatibility studies with other drugs) PIL

Question 8

Adverse drug reaction (4 points)

Answer 8

Micromedex
Uptodate Lexicomp
Meyler’s Side Effect of Drugs
PIL

Question 9

Drug Drug interaction (4 points)

Answer 9

Micromedex
Uptodate Lexicomp
Stockley’s DI
University of Liverpool DI

Question 10

Definition of neonates

Why are neonates and premature infants at greater risk of toxicity?

Answer 10

Less than 4 weeks old

Due to immature excretory functions, causing drug accumulation

Question 11

What is relative infant dose?

What is the formula?

What is a safe RID level?

Answer 11

Extent of maternal dose that infant is receiving

Infant dose in milk (mg/kg/day) / Maternal dose (mg/kg/day) x 100%

RID < 10% is probably safe