drug info

Question 1

what gives thepharmcoligcal response

Answer 1

neurotransmitter and agnoist!

Question 2

what does not give the pharmacolical response?

Answer 2

Antagonist

Question 3

what is the function of antibiotics:

Answer 3

damages the bacteria cell wall
modifies protein synthesis of organism
modifies organism’s metabolism
modifies DNA synthesis

Question 4

the drug-receptor binding site can be

Answer 4

strong or less strong (narcan vs. morphine
reversible (ibuprofen, ,motrin)
irreversible (aspriin on platelets)

Question 5

What is analgesics

Answer 5

transmission of pain: nerve fibers carry pain impulses from the body’s receptor sites through the spinal cord and up to the thalamus and cerebral corex

Question 6

analgesics

Answer 6

centrally acting: dulls receptor in brain more narotic
peripherally acting
vs. local anesthesia MOA

Question 7

common administration routes

Answer 7

injectable (intravenous, subcutaneous, intramuscular)
oral
reecctal

Question 8

what is a less common route

Answer 8

sublingual
topical/transdermal
inhalation
injectable
enteral

Question 9

bioavailability

Answer 9

percentage of drugs that reach the general bloodsream

Question 10

first pass effect

Answer 10

after absorption from gastrointestinal tract, the drug is first carried through the liver where it migt be matabolized/destroyed prior

Question 11

Parenteral

Answer 11

defines the most common method of drugadministration that do not use the GI tract

Question 12

Metabolism (enzymatic alteration of drug)

PRIMARY AND LIMITED

Answer 12

hepatic (liver)
renal(kidney)
gastrointestinal
circulating enzymes

Question 13

Excretion (elimination often of water soluble chemicals)

PRIMARY

Answer 13

renal (kidney)
gastrointestinal
pulmonary (lungs)
dermal (skin)

Question 14

Hepatic (liver) phases (1)

Answer 14

Phase 1: oxidation – water soluble)

caalyzed by cytochrome P450