Drug Groups And Therapeutic Purpose

Question 0

Anticholinergic agents

Answer 0

A-adrenergic: Topical vasoconstriction and decongestion. Relaxation of cholinergically induced bronchoconstriction to improve ventilatory flow rates in COPD and asthma.

Epinephrine
Ipratropium bromide
Tiotropium bromide

Question 1

Adrenergic agents

Answer 1

B-adrenergic: relaxation of bronchial smooth muscle and bronchodilation, to reduce RAW and to improve ventilatory flow rates in airway obstruction resulting from, e.g., COPD, asthma, CF, acute bronchitis.

Albuterol
Arformoterol
Formoteral
Isoetharine
Levalbuterol
Metaproterenol
Pirbuterol
Salmeterol

Question 2

Mucoactive agents

Answer 2

Modification of the properties of respiratory tract mucus; current agents lower viscosity and promote clearance of secretions.

Acetylcysteine
Dornase alfa

Question 3

Corticosteroids

Answer 3

Reduction and control of airway inflammatory response usually associated with asthma (lower respiratory tract) or with seasonal or chronic rhinitis (upper respiratory tract)

Beclomethasone dipropionate
Budesonide
Ciclesonide
Flunisolide
Fluticasone propionate
Mometasone furoate
Triamcinolone acetonide

Question 4

Anti asthmatic agents

Answer 4

Prevention of the onset and development of the asthmatic response, through inhibition of chemical mediators of inflammation.

Cromolyn sodium
Montelukast
Nedocromil sodium
Zafurlukast
Zileuton

Question 5

Anti-infective agents

Answer 5

Inhibition or eradication of specific infective agents, such as pnuemocystis carinii (jiroveci) (pentamidine), respiratory syncytial virus (ribavirin), Pseudomonas aeruginosa in CF or influenza A and B

Pentamidine
Ribavirin
Tobramycin
Zanamivir

Question 6

Exogenous surfactants

Answer 6

Approved clinical use is by direct intratracheal instillation, for the purpose of restoring more normal lung compliance in respiratory distress syndrome of newborns.

Beractant
Calfactant
Poractant alfa