Drug Groups Flashcards
1
Q
QT PROLONGATION DRUGS
A
Antiarrythmics: • Amiodarone, Dronedarone • Sotalol • Flecainide • Disopyramide Antidepressants: • Citalopram • Escitalopram • Clomipramine • Venlafaxine Antipsychotics: • Haloperidol • Chlorpromazine • Risperidone • Amisulpride • Sulpride • Pimozide • Paliperidone • Zuclopenthixol Antimalarial: • Quinine, hydroxychloroquine Other: • Apomorphine • Clarithromycin, erythromycin • Moxifloxacin • Fluconazole, Voriconazole • Hydroxyzine • Lithium • Methadone • Ranolazine • Sildenafil • Tolterodine • Domperidone • Ondansetron • Droperidol • Levomepromazine
2
Q
ANTICHOLINERGIC DRUGS
A
Antiarrhythmics: • Procainamide • Disopyramide • Propafenone Antihistamines: • Chlorphenamine • Diphenhydramine • Promethazine Antidepressants: • Amitriptyline • Nortriptyline • Dosulepin • Doxepin • Clomipramine Antipsychotics: • Chlorpromazine • Clozapine • Olanzapine • Haloperidol • Pimozide Antiparkinsonism: • Amantadine • Procyclidine Antiemetics: • Hyoscine hydrobromide • Prochlorperazine • Cyclizine • Levomepromazine Antispasmodics: • Hyoscine butylbromide • Propantheline • Dicycloverine Bronchodilators: • Ipratropium • Tiotropium • Glycopyrronium • Umeclidinium • Aclidinium Drugs for urinary frequency, enuresis, and incontinence: • Flavoxate • Oxybutynin • Solifenacin • Tolterodine • Darifenacin • Trospium • Propiverine Others: • Atropine • Baclofen • Hydroxyzine • Nefopam
3
Q
SEROTONIN SYNDROME DRUGS
A
- SSRI
- SNRI
- Triptans
- Bupropion
- Selegiline
- Ondansetron
- Methadone
- Mirtazapine
- Moclobemide
- Fentanyl
- Lisdexmfetamine
- Dexamphetamine
- Lithium
- Tramadol
- Tapentadol
- Trazodone
- St john’s wort
- Isocarboxazid
- Pethidine
- Phenelzine
- Imipramine
- Rasagiline
- Linezolid
4
Q
DRUG INDUCED HYPERGLYCAEMIA
A
‘B-CATS’
- BB
- CORTICOSTEROIDS
- ANTIPSYCHOTICS
- THIAZIDE DIURETICS
- STATINS
5
Q
DRUGS THAT COLOUR BODILY FLUIDS
A
- Senna= Yellow/red
- Sulfasalazine = Yellow/orange
- Nefopam = pink
- Phenindione = pink/orange
- Rifampicin = orange/red
- Rifabutin= orange/red
- Entacapone= red/brown
- Nitrofurantoin= red/brown
- Deferiprone =red/brown
- Levodopa= red
- Clofazimine= red
- Dantron preps= red
- Triamterene preps = blue
6
Q
DRUGS THAT INCREASE RISK OF BLEEDING
A
- NSAIDS
- Anticoagulants
- Antiplatelets
- SSRIS
- SNRIS
- Nicotinic acid
- Thrombolytics
- Omega 3 acid ethyl esters
7
Q
BLOOD DYSCRASIA DRUGS
A
- Azathioprine- Bone marrow suppression
- Aminosalicylate (Mesalazine, sulfasalazine)
- Carbamazepine
- Carbimazole
- Co-trimoxazole (discontinue immediately)
- Ethosuximide
- Isoniazid
- Methotrexate
- Mirtazapine
- Penicillamine
- Phenytoin
- Sodium valproate
- Trimethoprim
8
Q
CNS DEPRESSANT EFFECT DRUGS
A
- Antipsychotics
- Alcohol
- Baclofen
- Benzodiazepines
- Clonidine
- Clomethiazole
- Lamotrigine
- Opioids
- TCAs
- Sedatives (zopiclone, zolpidem)
- Sedative antihistamines
9
Q
PHOTOTOXICITY DRUGS
A
Piroxicam
• Patients should wash hands immediately after use
• Photosensitivity- avoid excessive exposure to sun
Chlorpromazine
• Risk of contact sensitisation- avoid direct contact. Tablets should not be crushed, solutions should be handled with care
• Photosensitisation- Avoid direct sunlight
Clozapine- photosensitisation
Doxycycline
• Photosensitivity
Amiodarone
• Avoid direct sunlight. Apply wide spectrum UV cream
10
Q
BRADYCARDIA DRUGS
A
- Digoxin
- CCBs (vera/diltiazem)
- BBs& Alpha blockers
- Antiarrhythmics
- Anticholinesterase inhibitors
- Ivabradine
- Mefloquine
- Selegiline
- Ticagrelor
- Fentanyl
11
Q
HYPOTENSIVE DRUGS
A
- Apomorphine
- Alcohol
- Antipsychotics
- Antihypertensives
- Antiparkinsonism drugs
- Baclofen
- Phosphodiesterase inhibitors
- TCAs
12
Q
NEPHROTOXIC DRUGS
A
ACE inhibitors ARBs Diuretics Aminoglycosides Vancomycin Nitrofurantoin Trimethoprim Tetracycline Ciclosporin Tacrolimus Methotrexate Lithium NSAIDs Metformin
13
Q
Enzyme inducers
A
CRAP-GPS
- Carbamazepine
- Rifampicin
- Alcohol
- Phenobarbital
- Griseofulvin
- Phenytoin
- Smoking
- St johns wort
14
Q
Enzyme inhibitors
A
'SICK FFACE COM G' • SV • Isoniazide • Cimetidine • Ketoconazole • Fluconazole/ Fluoxetine • Alcohol • Chloramphenicol • Erythromycin • Ciprofloxacin • Omeprazole • Metronidazole • Grapefruit juice
15
Q
DRUG INDUCED CONSTIPATION
A
- Antispasmodics (Dicycloverine, mebeverine, peppermint oil)
- Antiepileptics (Carbamazepine, oxcarbazepine, phenytoin, pregabalin)
- Antihypertensives (Clonidine, methyldopa, propranolol, verapamil).
- Antihistamines (Chlorphenamine, promethazine)
- Antipsychotics= Amisulpride, chlorpromazine, clozapine
- Tricyclic antidepressants (amitriptyline, Dosulepin, imipramine)
- MAOIs (moclobemide, phenelzine)
- Antiparkinsonism= entacapone, pramipexole, procyclidine, selegiline
- Iron preparations
- Bisphosphonates (alendronic acid and risedronate)
- Alpha blockers e.g. prazosin, tamsulosin
- Aluminium containing antacids
- Cholestyramine
- Furosemide
- Opioids
