Drug Group 2A

Question 1

Albuterol Sulfate

Class

Answer 1

-Sympathomimetic (mimic or stimulate the adrenergic nervous system)

-Bronchodilator (widening of the bronchi)

Question 2

Albuterol Sulfate

MOA

Answer 2

-B2 agonist (relaxes smooth muscle lining of airways, results in bronchodilation)

-Decreased airway resistance

Question 3

Albuterol Sulfate

Indications

Answer 3

-Treatment of bronchospasms (tightening of the muscles that line the airway (bronchi) in your lungs.

Question 4

Albuterol Sulfate

Adult Dose & Route

Answer 4

-Bronchospasms: 2.5mg via SVN or in-line with BVM, CPAP or Ventilator, repeat as needed in 20 mins.

Question 5

Albuterol Sulfate

Onset of Action

Peak Effect

Duration of Action

Answer 5

Onset- 5-15 min

Peak- 1 - 1.5 hours

Duration- 3-6 hours

Question 6

Ipratropium Bromide (Atrovent)

Class

Answer 6

• Anticholingeric (block the action of the neurotransmitter called acetylcholine (ACh) at synapses in the central and peripheral nervous system).

-Bronchodilator (widening of the bronchi)

Question 7

Ipratropium Bromide (Atrovent)

MOA

Answer 7

-Anticholingeric (parasympathetic) agent that inhibits vagally-mediated reflexes.

Question 8

Ipratropium Bromide (Atrovent)

Indications

Answer 8

-Treatment of bronchospasms associated with COPD.

Question 9

Ipratropium Bromide (Atrovent)

Adult Dose & Route

Answer 9

-250-500 mcg (0.25-0.5mg) via SVN or in-line with BVM, may repeat every 20 mins up to 3 times.

Question 10

Ipratropium Bromide (Atrovent)

Onset of Action

Peak Effect

Duration of Action

Answer 10

Onset- 5-15 mins.

Peak- 1.5 - 2 hours

Duration- 4-6 hours

Question 11

Methylprednisolone Sodium Succinate (Solu-Medrol)

Class

Answer 11

-Corticosteroid (class of steroid hormones that are produced in the adrenal cortex or made synthetically).

-Anti-Inflammatory (reduce redness, swelling, pain).

Question 12

Methylprednisolone Sodium Succinate (Solu-Medrol)

MOA

Answer 12

-Enters target cells and produces anti-inflammatory and immunosuppressive effects.

-Stabilizes cellular membrane.

Question 13

Methylprednisolone Sodium Succinate (Solu-Medrol)

Indications

Answer 13

-Reactive airway disease (RAD), acute emphysema exacerbation, chronic bronchitis, asthma

-Anaphylaxis

-Burns potentially involving the airway

Question 14

Methylprednisolone Sodium Succinate (Solu-Medrol)

Adult Dose & Route

Answer 14

• 1-2 mg/kg IV/IO/IM slow push (max dose 125 mg)

Question 15

Methylprednisolone Sodium Succinate (Solu-Medrol)

Onset of Action

Peak Effect

Duration of Action

Answer 15

Onset- 1-6 hours

Peak- 8 hours

Duration- 18-36 hours

Question 16

Dexamethasone Sodium Phosphate (Decadron)

Class

Answer 16

-Synthetic adrenalcorticosteroid/glucocorticoid

-Anti-Inflammatory

Question 17

Dexamethasone Sodium Phosphate (Decadron)

MOA

Answer 17

-Improves lung function & myocardial performance
-Stabilization of cell membrane
-Increased surfactant production, decreased pulmonary edema
-Relaxation of bronchospasms

Question 18

Dexamethasone Sodium Phosphate (Decadron)

Indications

Answer 18

-Reactive airway disease (RAD), acute asthma exacerbation

-Stridor secondary to anaphylaxis

Question 19

Dexamethasone Sodium Phosphate (Decadron)

Adult Dose & Route

Answer 19

-Bronchospasms: 1mg/kg slow IV/IO (max dose 16 mg)

Question 20

Dexamethasone Sodium Phosphate (Decadron)

Onset of Action

Peak effect

Duration of Action

Answer 20

Onset- 4-8 hours

Peak- 6-12 hours

Duration- 24-72 hours