Drug Drawer Flashcards
Albuterol
Drug Class: SympathomimeticEffect: Bronchial RelaxationMechanism: Selective beta2 adrenergic agonistPeak Effect: 30-60 minutesDuration of Action: 4 hoursConcentration: 90mcg/puffDose: 2 puffs during deep inhalation every 4-6 hours.Method of Administration: Metered Dose Inhaler, OralIndications: Wheezing, bronchospasmContraindications: Tachydysrhythmias
Amiodarone
Drug Class: Antidysrhythmic Class 3Effect: Block potassium ion channels resulting in prolonged depolarization, action potential duration, and the effective refractory period.Mechanism: Sodium channel blockade (class 1), Beta-blockade (class 2), and calcium channel blockade (class 4)Duration of Action: 4 hoursDose: Can give 5mg/kg over 2-5 minDose (common): 150 mg IV loading dose over 10 minutes, followed by 1mg/min IV for 6 hours, and 0.5mg/min IV for 18 hours after.Indications: Ventricular Tachycardia, Ventricular Fibrillation.
Atropine
Drug Class: Anticholinergic DrugMechanism: Muscarinic receptor antagonists. Antagonistically inhibits parasympathetic nerve conduction.Onset: 1 minuteDuration of action: 30-60 minutesDose: For bradycardia 0.4-0.6 mg (up to 3mg)
Calcium Chloride
Drug Class: Electrolyte ReplacementMechanism of action:Increase the force of cardiac contractility, by initiating myofibril shortening.Effect: In normally functioning hearts calcium will produce positive inotropic and vasoconstrictive effects and increase systemic arterial blood pressure. In abnormally functioning hearts calcium will produce positive inotropic effects may increase or decrease systemic vascular resistance. It also appears to increase ventricular automaticity.Duration of Action: 10-20 minutesDose: 5-10 mg/kg IVIndications: Hyperkalemia, hypermagnesemia, hypocalcemia.Contraindications: Hypercalcemia, digitalis toxicity.
Cefazolin
Drug Class: First Generation CephalosporinEffect: Prevent infectionDuration of Action: Redosed 2-6 hoursDose: 1-2g IV (>50kg is 2g)Contraindication: Penicillin allergy
Cefoxitin
Drug Class: Second Generation CephalosporinEffect: Prevent InfectionDuration of Action: Redosed 2-6 hoursDose: 2g IVContraindication: Penicillin AllergyMechanism: Extended activity against gram-negative bacteria. Resistant to produced cephalosporinases
Cleocin Phosphate (converts to clindamycin)
Drug Class: Macrolide AntimicrobialEffect: Prevent and treat infection, particularly effective in GI tract and female genital tractDuration of Action: Redose every 6 hoursDose: 600 or 900mg IV infusionIndication: Penicillin Allergy
Dexamethasone (decadron)
Drug Class: CorticosteroidEffect: Reduce swelling, prevent PONVDuration of Action: Half-life 3 hours, effects last as long as 24 hours.Dose: 4-8mg PONVDon’t give pre-op if possible, causes peri-anal itching.Contraindications: Systemic Fungal Infection
Diphenhydramine (benadryl)
Drug Class: AntihistamineEffect: Prevent histamine releaseMechanism of Action: Histamine receptor antagonist.Duration of action: 3-6 hoursDose: 25-50mg IVIndications: Anaphylaxis, allergic reaction, PONV, histamine release, redman syndrome.Contraindications: Acute asthma attack, lower respiratory tract disease. Nursing mothers
Ephedrine
Drug Class: Synthetic non-catecholamineEffect: Increase blood pressure and heart rateMechanism of Action: Mostly indirect stimulation of the release of norepinephrine, stimulating alpha receptors. Some direct stimulation of beta receptors as well.Dose: 5-20 mgCaution: Tachyphylaxis (you will see diminishing affects with each subsequent dose as norepinephrine is depleted)
Epinephrine
Drug Class: CatecholamineUse: Increase Heart rate and Blood pressure, Anaphylaxis, bronchospasmSupplied: 16mcg/mL and 4mcg/mLDose: 8-16mcgInfusion: 1-2mcg/min - Beta 2 receptors4mcg/min - Beta 110-20mcg/min alpha and beta
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Look for this drug in the cart
Etomidate (amidate)
Drug Class: Imidazole Induction AgentUse: Induction/HypnosisSupplied: 2mg/mL (35% propylene glycol)Dose: 0.2-0.3mg/kgIndication: Unstable/weak cardiovascular system
Fentanyl
Drug Class: Synthetic OpioidUse: AnalgesiaSupplied: 50mcg/mLPeak Effect: 3-5 minutesDuration: 30-60 minutesDose: 1-2mcg/kgInfusion: 1-2mcg/kg/hrCaution: Synergism with Midazolam
Furosemide
Drug Class: DiureticUse: Severe essential hypertension, edema due to congestive heart failure, renal failure, and hepatic failureMechanism of Action: Inhibit reabsorption of sodium and chloride in the medullary portions of the ascending limbs of the loops of Henle.Dose: 0.1-1mg/kg IV for edema 0.5-1.0 mg/kg IV for increased ICP