ANes Pharm - ANtibiotics

Question 1

1st Generation cephalosporin

Answer 1

least spectrum of coverage. Mostly Gram + (cefazolin)

Question 2

2nd Generation cephalosporin

Answer 2

Have more gram - coverage. (cefoxitin, cefurxoime, cefaclor)

Question 3

3rd generation cephalosporin

Answer 3

ceftriaxone and ceptizoxime

Question 4

4th generation cephalosporin

Answer 4

Broadest spectrum of coverage. Gram - and gram +. (Maxiprime ane Cefelidine)

Question 5

Bactericidal

Answer 5

Activly kill microrganisms

cephalosporins, aminglycosides, fluoroquinolones, vancomycin, daptomycin, metronidazole

Question 6

Bacteriostatic

Answer 6

Slow groth of microorganisms

macrolides, tetracyclines, trimethoprim, sulfonamides

Question 7

Cephalosporin

Answer 7

B-lactum ring inhibits cell wall synthesis

Question 8

Clean procedures

Answer 8

Cefalozin 1-2 g

Question 9

Thoracic / orthopedic

Answer 9

Ceuroxime 1.5g

Question 10

Bowel

Answer 10

Cefoxitan 1-2g or Cefazolin 1-2 g + metronidazole 500mg, Ampicillin / sublactam 3g

Question 11

PCN allergies

Answer 11

Vancomycin 1g or Clindamycin 600-900mg

Gram - coverage may be added w gentamycin, cipro, levo and aztreonam

Question 12

Vancomycin

Answer 12

inhibits cell wall synthesis. Most gram + 15mg/kg. prevention of MRSA, prostetic heart valve and vascular graft. Caution VRE. Redose 12hrs.

Question 13

Neurosurgey

Answer 13

Cefazolin 1-2g. Nafcillin 1-2g. Vanco 1g.

Question 14

Head and Neck

Answer 14

Cefazolin 1-3g or Clindamycin 600-900mg + gent 1.5mg/kg

Question 15

Cardiac Surgery

Answer 15

Cefuoxime. Vanc and clin are alternatives.

Question 16

Noncardiac thoracic surgery

Answer 16

Cefazolin 1-2g. Cefuroxime 1.5g. Vanco 1g w/ MRSA. Clin 600-900mg alternative for B-lactum allergy

Question 17

Colorectal Surgery

Answer 17

Oral - Neomycin 1g + erythromycin 1g