Drug Dosing Flashcards

1
Q

IV intubating dose of succinylcholine:

A

1.0 - 1.5 mg/kg
duration 12-15 minutes on average til full neuromuscular recovery

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2
Q

Discuss IM midazolam onset and duration of action:

A

IM onset: 3-5 minutes
peak effect: 10-20 minutes
wait at least 20 minutes before considering giving a supplemental dose of midazolam

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3
Q

What is the usual concentration of epinephrine added into local anesthetics to prolong epidurla blockade?

A

1:200,000
aka
5 mcg/ml

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4
Q

T10 subarachnoid block dose in mg for bupivacaine 0.5-0.75% or levobupivacaine 0.5%

A

10-15 mg
onset 4-8 min
duration 130-220 min
bupi w/ epi duration +20-50%

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5
Q

T4 subarachnoid block dose in mg for bupivacaine 0.5-0.75% or levobupivacaine 0.5%

A

12-20 mg
onset 4-8 min
duration 130-220 min
bupi w/ epi duration +20-50%

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6
Q

T10 subarachnoid block dose in mg for ropivacaine 0.5-1%

A

12-18 mg
onset 3-8 min
duration 80-210 min

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7
Q

T4 subarachnoid block dose in mg for ropivacaine 0.5-1%

A

18-25 mg
onset 3-8 min
duration 80-210 min

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8
Q

T10 subarachnoid block dose in mg for 2-chloroprocaine 3%

A

30-40 mg
onset 2-4 min
duration 40-90 min

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9
Q

T4 subarachnoid block dose in mg for 2-chloroprocaine 3%

A

40-60 mg
onset 2-4 min
duration 40-90 min

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10
Q

T10 subarachnoid block dose in mg for tetracaine 0.5-1%

A

6-10 mg
onset 3-5 min
duration 90-120 min
with epi duration + 20-50%

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11
Q

T4 subarachnoid block dose in mg for tetracaine 0.5-1%

A

12-16 mg
onset 3-5 min
duration 90-120 min
with epi duration + 20-50%

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12
Q

Epidural concentration, onset, duration: 2-chloroprocaine

A

3%
5-15 min
30-90 min

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13
Q

Epidural concentration, onset, duration: lidocaine

A

2%
10-20 min
60-120 min

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14
Q

Epidural concentration, onset, duration: ropivacaine

A

0.1-0.75%
15-20 min
140-220 min

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15
Q

Epidural concentration, onset, duration: bupivacaine and levobupivacaine

A

0.0625-0.5%
15-20 min
160-220 min - bupi
150-225 min - levobupi

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16
Q

Reversal agent dosing based on TOF: edrophonium

A

TOF 4 w/o fade = 0.5 mg/kg
TOF 3-4 with fade = 0.5 mg/kg
TOF 1-2 = 1-1.5 mg/kg
TOF < 1 = not indicated

17
Q

Reversal agent dosing based on TOF: pyridostigmine

A

TOF 4 w/o fade = 0.2 mg/kg
TOF 3-4 w/ fade = 0.2 mg/kg
TOF 1-2 = 0.35 mg/kg
TOF < 1 = not indicated

18
Q

Reversal agent dosing based on TOF: neostigmine

A

TOF 4 w/o fade = 0.02 mg/kg
TOF 3-4 w/ fade = 0.04 - 0.05 mg/kg
TOF 1-2 = 0.07 mg/kg
TOF < 1 = not indicated