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Pharm test II > Drug/DOC (prim use)/prim adverse effects > Flashcards

Drug/DOC (prim use)/prim adverse effects Flashcards

1
Q

Heparin

A

Ind: IV anticoagulation
PAE: bleeding

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2
Q

Enoxaprin

A

Ind: DVT/PE prophylaxis in pregnancy

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3
Q

Warfarin

A

DOC:Chronic DVT/PE prophylaxis

Cat X in prenancy

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4
Q

Plavix

A

Ind: platelet inhibhition in stenting

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5
Q

t-PA

A

clot busting-DVT, PE

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6
Q

Aminocaproic acid

A

DOC: reverse t-PA
PAE: thrombosis

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7
Q

Aspirin

A

DOC: primary MI prevention
PAE: irreversibly binds PGs

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8
Q

Bile resins

A

SAFEST HYPERLIPIDEMIA med

no effect on triglycerides, increases VLDL

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9
Q

Niacin

A

MOST EFFECTIVE AGENT for increasing HDL

decreases VLDL & decreases LDL

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10
Q

Statins

A

DOC: most effective at decreaseing LDL
PAE: liver damage, rhabdomylolysis

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11
Q

Fibrates

A

Ind: most effective at decreasing triglycerides
PAE: decreases LDL, gemfibrizol blocks statins

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12
Q

Zetia

A

Ind: decrease LDL, synergistic with statins

no AEs

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13
Q

Quinidine

A

Ind: Acute & chronic supraventricular & ventricular arrhythmia
PAE: syncope, wide QT-I, cinchonism

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14
Q

Lidocaine

A

DOC: acute ventricular arrhythmia

IV only

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15
Q

Flecainamide

A

LAST DITCH ANTI-ARRYTHMIC

strongly pro-arrhythmic

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16
Q

Amiodarone

A

DOC: CHRONIC ventricular arrhythmia (stable V tach)

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17
Q

Verapamil

A

high heart effects w/low vessel effect

DO NOT MIX W/B-BLOCKERS

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18
Q

Dilatezem

A

moderate heart & vessel effects-PSVT

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19
Q

Adenosine

A

DOC: acute PVST, WPW
PAE: flushing

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20
Q

Magensium

A

DOC: Torsades de Pointes

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21
Q

Potassium

A

DOC: Digoxin toxicity

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22
Q

Acetolamide

A

alkalinzation of urine

hyperuricemia

23
Q

Dorzolamide

A

closed angle gluacoma

24
Q

Brinzolamide

A

a carbonic anhydrase inhibitor with no mentioned DOC or PAE on this nice beginning dropbox chart

25
Q

Furosemide

A

Ind:MOST EFFECTIVE DIURETIC-CHF, edema, hypercalcemia, PE (w/morphine)
PAEs: sulfonamide rxn, hypokalemic metabolic alkalosis, hypochloremia, hypocalcemia and hypomagnesemia, hyperuricemia

26
Q

Ethacrinic acid

A

NONSULFAMIDE loop

highest risk of OTOTOXICITY

27
Q

Thiazides

A

DOC: HTN; vasodilation due to PG synthesis
PAEs: decreases insulin secretion, hyperglycemia, hypokalemia, hyperuricemia, hypomagnesemia, elevated serum lipids (except indapamide)

28
Q

Metolazone

A

sim to thiazides, used in LOW GFR pts (t, except metolazone]

29
Q

Indapamide

A

thiazide for ppl w/renal problems
metabolized by liver, excreted in bile
DOSEN”T INCREASE PLASMA LIPIDS

30
Q

Spironolactetone

A

[competitive inhibitor of aldosterone]
Ind: HYPERALDOSTERONISM
can use w/pts on thiazides instead of supplementing K
caution w/ARB/ACE-I, hyperkalemia

31
Q

Amiloride

A

DOC: Li-induced diabetes insipidus

NO hyperuricemia, NOT AN ACID (Amiloride and Trimatrene are the only NONACIDS)

32
Q

Osmotics-mannitol

A

diuresis in AKD, decrease IOP, decrease ICP

33
Q

Desmopressin

A

central diabetes insipidus

34
Q

Conivaptan

A

Euvolemic/hypervolemic hyponatremia

35
Q

Lithium

A

Hyponatremia

36
Q

Demeclocycline

A

SIADH

37
Q

Digoxin

A

CHF/HTN
decreases notmal tone via NaKATPase dec. HR, inc.CO, inc. contractility, increases BP
incCO=inc baroreflex-dec. SNS=vasodilation
PAE: bigemini, toxicity (GI early), blue vision, norrow therapeutic range
Toxicity: inc Ca & dec. K

38
Q

Dopamine

A

end stage CHF-beta1 specific

decreased filling, increased oxygen consumption

39
Q

ACE-I (-prils)

ARBs (-sartans)

A

DOC: HTN & CHF (decreases mortality), increase diuretic effectiveness
PAEs: ACE-I=cough
hyperkalemia

40
Q

alpha blocker (-zosins)

A

BPH

PAE: first dose phenomenon

41
Q

Esmolol

A

short acting cardioselective beta blocker

42
Q

Clonidine

A

HTN

NOT for MONOTHERAPY

43
Q

Methyldopa

A

HTN in pregnancy

hemolytic anemia w/ (+) combs

44
Q

Labetolol

A

HTN emergencies w/o reflex tachycardia

hepatotoxic

45
Q

Hydralazine_isosorbide dinitrate

A

Best HTN in African americans

PAE: HIP drug

46
Q

Sodium nitroprusside

A

IV HTN emergencies

PAE: cyanide buildup & toxicity

47
Q

Minoxidil

A

chronic HTN

hair growth

48
Q

Fenoldopam

A

HTN emergencies via renal vasculature

49
Q

Dihydropyridines

A

CCDs-vasodilation w/less heart effect

DO NOT USE IN CHF

50
Q

Nefidiine

A

high vessel effect w/low heart effect

PAE: gingival hyperplasia

51
Q

Diltiazem

A

moderate heart & vessel effects-PSVT

52
Q

Verapamil

A

High heart effects w/low vessel effect

PAE: constipation

53
Q

Nitrates+CCBs

A

DOC Prinzmetals

54
Q

Nitrates

A

DOC Acute Angina

PAD: tolerance

Pharm test II (6 decks)

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