Drug Development- Uses Of Monoclonal Antibodies Flashcards
What can monoclonal antibodies be used for?
Pregancy test, treating cancer, diagnosis of disease.
What is the 1st stage of pregancy tests?
Reaction zone- Antibodies grab onto HCG. They are enzymes which turn on dye molecules.
What is the 2nd stage of pregancy tests?
Test zone- Theres are more antibodies that stick onto the HCGs callled a sandwich assay. The dye molecules let out paint which makes the line red.
What is the 3rd stage of pregancy tests?
Control zone- All the unbound enzymes release the dye at this zone.
How many lines does a positive test contain?
2
How do monoclonal antibodies allow doctors to diagnose diseases?
Monoclonal antibodies can be made which bind on to specific antigens on blood clots or cancer cells. The Monoclonal antibodies can also carry markers which makes it easy for doctors to see where they have built up.
How do Monoclonal antibodies allow doctors to treat disease?
Monoclonal antibodies can be used to carry drugs to specific tissues because they bind to antigens in a tumour. This will stop the cell from growing and dividing.
What is an advantage of Monoclonal antibodies?
They only affect specific cancer cells and won’t hurt healthy cells.
What is a disadvantage of Monoclonal antibodies?
They can have lots of side effects and can be expensive to produce.