Drug Delivery Route Flashcards

1
Q

Examples of drug delivery

A

Eternal,
local,
parenteral,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Examples of eternal drug delivery

A

Capsules, tablets, sublingual, caplets feeding tube, enteric coated, and suppositories

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Advantages of enteric drug delivery?

A

Safe, self administered, convenient, economical, and no invasive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Disadvantages of enteric drug delivery?

A

Slow on set of action, possible GI irritation, cannot be given to unconscious or uncooperative patients and may undergo extensive first pass metabolism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Examples of parenteral drug delivery

A

Internal, intravenous (IV), intramuscular(IM), inhalation, subcutaneous, transdermal, and transmucosal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Parenteral ophthalmic injection examples

A

Retrobulbar, sub conjunctiva, intracameral, intravitreal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Advantages of parenteral drug delivery

A

Rapid action, more predictable action, ease of administration to unconscious pts, avoid first pass metabolism, and avoids GI irritation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Disadvantages of parental drug delivery

A

May be painful, May damage nerve/ tissue, expensive, less safe, and asepsis must be maintained

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Examples of local drug delivery

A

Ointment, cream, gel, paste, mucous membrane, and powder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Advantages of local drug delivery

A
  1. Low risk of systematic adverse effects
  2. Low risk of drug interactions
  3. Small amount of drug used
  4. Low coast
  5. Avoids first pass metabolism
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Disadvantages of local drug delivery

A

Potential allergic contact dermatitis
Penetrates only targeted areas
Skin type impacts absorption speedy
Time consuming to apply

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Advantages of innovative drug delivery

A

Improve compliance
Drug stays in the tissue even after the lens is removal
Continues drug delivery
Avoids need for surgery or drops
Not very invasive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the concerns of innovative drug delivery

A

Cost,
contact lens intolerance
Risk of infection
Type of delivery
Parenteral or topical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the three key steps of meditation instillation

A

Wash hands
Place cup in clean area
Do not touch tip of bottle/tube to eye

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the cap colour of antibiotics

A

Tan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the cap colour of anti-inflammatory or steroid?

A

Pink

17
Q

What is the cap colour of mydiatics or cyclopegics?

A

Red

18
Q

What’s the cap colour of beta-blockers?

A

Yellow

19
Q

What is the cap colour of beta- blocker combination?

A

Dark blue

20
Q

What’s the colour of adrenergic agonists?

A

Purple

21
Q

What’s the cap colour of Miotics?

A

Dark green

22
Q

What’s the cap colour of Nonstroidal anti-inflammation?

A

Grey

23
Q

What’s the cap colour of carbonic anhydrase inhibitors?

A

Orange

24
Q

What’s the cap colour of Prostaglandin analogues

A

Turquoise

25
Q

Examples of OTC ophthalmic products

A

Artificial tears
ophthalmic vitamins
Contact lens solution
Antimicrobials
Diagnostic dyes
Hyperosmotics
Mast cell stabilizers
Antihistamine
Sympathomimetic decongestants

26
Q

What are the group 5 OTC products and used for?

A

Box indicates treatment of allergies Mast cell stabilizer
Used: histamine release
Product examp: opticrom and cromolyn eye drops

27
Q

Examples of OTC group 7 products?

A

Multi vitamins
Used: slow macular degeneration and manage dry eyes
Product examp: ocuvite, vitalux, and De(dry eye omega benefits)

28
Q

What are the ophthalmic adverse drug reactions for Bleph-10 (sulpha drug)

A

Skin irritation
Itching
Rashes
Allergic reactions

29
Q

Ophthalmic adverse drug reaction for pred forte/ maxidex

A

Elevated intraocular pressure (risk of glaucoma

30
Q

Ophthalmic adverse drug reaction for mydriacyl(tropicamide) / cyclogyl (cyclopentolate)

A

Allergic tea
Tachycardia
Dry mouth
Headache
Nausea/vomiting
Flushed skin
Blurry vision
Photophobia

31
Q

Ophthalmic adverse drug reactions of alphagan (brimonidine) / iopidine ( apraclonidine)

A

Large reduction in blood pressure foreign body sensation, eyelid and conjunctival edema allergic reaction

32
Q

Ophthalmic adverse drug reactions of timoptic (timolol) / betoptic (betaxolol)

A

Contact dermatitis, hives, rashes, bradycardia, arrhythmias, hypotension, bronchospasm

33
Q

Causes of dry diseases

A

Aging,
medications,
digital devices.
environment,
contact lenses,
LASIK surgery,
meibomian gland dysfunction (MGD)
Blepharitis,
Reduced aqueous production

34
Q

Examples of MGD

A

Thickened meibum
Pool oil layer
Tear evaporation

35
Q

Treatment for MGD

A

Hot compresses
Expression of meibomian glands
Omega 3 supplements
Artificial tears
Medications
Lipiflow

36
Q

Types of contact lenses

A

Soft contact lenses,
Hard lenses
Speciality lenses
Gas permeable lenses

37
Q

Contact lens solution

A

Multipurpose solution (MPS)
Hydrogen peroxide solution
Gas permeable care system
Rewetting drops for improving comfort

38
Q

T/F Multi purpose contact lens solution cleans soft lenses

A

True

39
Q

Hydrogen peroxide CL solution cleans any type of lenses

A

True