Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

309 Unit 2 > 309 Unit 5 > Flashcards

309 Unit 5 Flashcards

1
Q

Anti infective drugs divided in four,

A

Antibacterials
Antivirals
Antifungal
Antiparasitic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Antibacterial terminology

A

Bactericidal
Bacteriostatic
Broad spectrum antibiotic
Narrow spectrum antibiotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Mechanism action of antibacterial

A

Inhibit folic acid synthesis
Inhibit DNA synthesis
Inhibit protein synthesis
Inhibit cell wall synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Mechanism of action of sulphonamides

A

Inhibit folic acid synthesis
Broad spectrum
Bacteriostatic
Ophthalmic use
Bacterial conjunctivitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Example drug of sulphonamides,

A

Blenheim-10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Adverse reaction of Bleph-10

A

Allergic reaction
Steven-Johnson syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Mechanism of action of fluoroquinolones,

A

Inhibit DNA synthesis
Broad spectrum
Bactericidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Drug examples for fluoroquinolones,

A

Ciloxan (Ciprofloxacin)
Vigamox (Moxifloxacin)
Moxeza (Besifloxacin)
Zymaxid ( Gaifloxacin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Adverse effects of fluoroquinolones,

A

Foreign body sensation
Itching and burning
Conjunctival hyperaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Mechanizing of action of fusidic acid

A

Inhibit protein synthesis
Bactericidal and Bacteriostatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Drug examples of fusidic acid,

A

Fusithalmic ( Fusidic acid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Adverse effects of fusithalmic ,

A

Stinging and irritation
Localized allergic reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Mechanism of action of Aminoglycosides

A

Inhibit protein synthesis
Bactericidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Drug examples of Aminoglycosides,

A

Tobrex ( Tobramycin)
Garamycin ( Gentamicin)
Neomycin ( Neomycin sulphate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Adverse effects of Aminoglycoside,

A

Type IV delayed hypersensitivity
Itching, redness, swelling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Mechanism of action of Macrolides,

A

Inhibit protein synthesis
Bactericidal or bacteriostatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Drug examples of Macrolides,

A

Odan-Erythromycin( Erythromycin)
AzaSite ( Azithromycin)

18
Q

Adverse affects of Macrolides,

A

Blurred vision
Allergic reactions

19
Q

Polypeptide antibiotic mechanism of action,

A

Interferes with cell wall synthesis
Bactericidal for gram positive bacteria
Infective against gram negative bacteria
Blepharitis

20
Q

Drug examples of polypeptide,

A

Ak-Tracin ( bacitracin)

21
Q

Adverse effects of Ak-Tracin

A

Allergic reactions

22
Q

Drug examples of combination antibacterials,

A

Polytrim ( trimethoprim and polymyxin B)
Polysporin ( bacitracin and polymyxin B)

23
Q

Adverse reactions of combination antibacterials

A

Allergic reactions

24
Q

Combination antibacterials mechanism of action,

A

Polymyxin B: breaks down cell membranes
Trimethoprim: prevents DNA synthesis
Bacitracin
Interferes with cell wall synthesis
Side note: though polymyxins are many applied to kill gram-negative pathogens, there are increasing reports showing their anti-gram- positive bacteria activity.

25
Q

Examples for antiviral drugs,

A

Herpes simplex virus(HSV) keratitis
Varicella zoster virus (VZV) keratitis
Used with oral antivirals

26
Q

Mechanism of action for topical antivirals

A

Inhibits synthesis of viral DNA

27
Q

Drug examples for antivirals

A

Viroptic ( trifluridine) 9x/day dosing
Zirgan ( Ganciclover) 5x/ day dosing

28
Q

Adverse effects of antivirals

A

Eye irritation
Conjunctival redness
Blurred vision
Punctuate keratitis

29
Q

Categories of Anti-fungal

A

Polyenes
Azoles
Anti metabolites

30
Q

Polyenes

A

Amphotericin B
Compounded product
Effective against yeasts and filamentary organisms

31
Q

Mechanism of action of Polyenes

A

Forms pores in cell wall membrane

32
Q

Example of Polyenes

A

Natacyn ( Natamycin)
Commercially Available
Poor ocular penetration
Effective against Aspergillus and fusarium

33
Q

Azoles

A

Oral antifungals with good ocular penetration
Inhibit cell wall synthesis

34
Q

Oral antifungal drug examples,

A

Ketoconazole
Fluconazole
Voriconazole

35
Q

Antimetabolites drug

A

Flucytosine

36
Q

Mechanism of action of flucytosine,

A

Inhibit DNA and RNA synthesis
Use in combination with Polyenes and Azoles

37
Q

Types of anti-parasitic treatment,

A

Treatment is lengthy
Treatment is difficult

38
Q

Anterior segment

A

Acanthamoeba
Protozoan
Swimming, pool, hot tub or contact lenses
Ring like corneal infiltrate

39
Q

Treatment options

A

Topical Neomycin
Polyhexamethylene biguanide ( PHMB)
Chlorhexidine

40
Q

Posterior segment

A

Toxoplasma Gondi
Protozoan
Chorioretinitis

309 Unit 2 (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions