Drug delivery Flashcards
1
Q
what are the factors affecting drug deposition in lungs
A
pt
device
formaulation
2
Q
what are the 4 groups affecting deposition in lungs
A
particle properties
aerosol properties
physiological properties
pt handling
3
Q
particle properties
A
size - mass median aerodynamic diameter
5um needed - ideal dilators
side effects - sedimentation, interception, electrostatic
4
Q
aerosol poperties
A
particle size range
evaporation of propellants
velocity of particles
5
Q
physiological properties
A
disease
mechanisms to keep drug out - mucous
6
Q
patient handling
A
proper technique
