Drug action at sympathetic nervous system Flashcards
1
Q
What is the sympathetic nervous system
A
Fight or flight
2
Q
What is released in each organ of the SNS
A
Noradrenaline is released in heart, airways, stomach and colon
HOWEVER:
Acetylcholine is released in sweat glands and adrenal medulla
3
Q
How to remove noradrenaline from synapse
A
Noradrenaline goes through the noradrenaline transporter and is put back into cytoplasm
4
Q
What drugs inhibit uptake of noradrenaline
A
Cocaine
Amphetamine
5
Q
What are the unwanted effects of cocaine
A
Heart - increase rate and force of contraction
Blood vessels - constrict (dilate)
Kindey - release renin = fluid volume
Urinary bladder - relaxes detrusor muscle
contracts sphincter muscle leading to urinary retention
6
Q
A
