Drug Action

Question 1

What happens in the phamaceutic phase?

Answer 1

The drug dissolves into a liquid

Question 2

optimal pH for dissolution

Answer 2

1-2

Question 3

excipients

Answer 3

gives color, shape, and flavor

Question 4

what is the pharmacokinetic phase?

Answer 4

what the body does to the drug

Question 5

list the 4 phases in the pharmacokinetic phase

Answer 5

absorption, distribution, metabolism, excretion

Question 6

where are most drugs absorbed?

Answer 6

small intestine

Question 7

what is the first pass effect?

Answer 7

drugs break down before being absorbed so a higher dose is required

Question 8

bioavailability

Answer 8

%of the drug in the circulatory system

Question 9

distribution?

Answer 9

getting to the tissue

Question 10

affinity

Answer 10

attractiveness

Question 11

what is the primary site for metabolism?

Answer 11

the liver

Question 12

creatinine clearance level?

Answer 12

normal 85-135 ml/min

Question 13

where does excretion take place?

Answer 13

the kidneys

Question 14

what is the pharmacodynamic phase?

Answer 14

how the drug affects the body

Question 15

list 4 types of actions drugs cause

Answer 15

stimulation or depression, replacement, inhibition/ death of organsims, irritation

Question 16

what is the trough level?

Answer 16

the time right before the next dose

Question 17

tachyphylaxis

Answer 17

acute tolerance to a drug