Dr. Davenport's lecture Flashcards
polar molecule
molecule that does not have an even distribution of charges
nonpolar molecule
molecule that has an even distribution of charges
lipid bilayer
a double layer of phospholipid molecules that have a polar/hydrophilic region (choline polar head group) and a nonpolar/hydrophobic region (fatty acyl chains), which separates intra and extracellular environments
what functions do proteins carry out in the cell membrane?
proteins make channels through the membrane for ions (conformation determines whether the channel is open or closed)
what is driving force?
something that provides the energy for a net movement of molecules from one solution to another
what is the relationship between cell permeability and lipid solubility?
cell permeability describes the ability of a molecule to cross the membrane. lipophilic molecules readily cross the cell membranes because they can traverse the lipophilic center (they’re nonpolar)
what is the resting membrane potential (RMP)?
the static membrane potential of relatively quiescent cell, caused by a semi-permeable membrane and a concentration gradient for ions. There will be a separation of charge if the membrane is impermeable to one ion. The situation will remain as long as the membrane conditions for the ions remain constant.
what is an action potential?
gated channels are responsible for pumping Na+ out of the cell and pumping K+ into the cell, against the net electrochemical gradient
what is electrochemical equilibrium?
when the concentration gradient equals the electrical gradient, which requires an ion selective semipermeable membrane
what is hyperpolarization?
when the RMP is becoming more negative
what is depolarization?
when the RMP is becoming less negative