DQ 4 todos

Question 1

Calcitriol

Answer 1

Vitamin D analog
hyperparathyroidism/hypocalcemia
binds to and activates the vitamin D receptor in kidney, parathyroid gland, intestine, and bone, stimulating intestinal calcium transport and absorption.

Question 2

Doxazosin Mesylate

Answer 2

Alpha-1 blocker
HTN, BPH
competitively inhibits postsynaptic alpha1-adrenergic receptors which results in vasodilation of veins and arterioles and a decrease in total peripheral resistance and blood pressure

Question 3

Drospirenone with Ethinyl Estradiol (21)

Answer 3

Contraceptive
Birth control
supress the LH and FSH resulting in the inhibition of ovulation

Question 4

Dutasteride

Answer 4

5 alpha-reductase inhibitor
BPH
competitive and selective inhibitor of both type 1 and type 2 isoforms of steroid 5-alpha-reductase (enz that converste testosterone to DHT)

Question 5

Estrogens (Conjugated)

Answer 5

Estrongen Derivative
Birth control
supressess release of FSH, LH, and luteotropic hormone due to an effect on the pituitary or hypothalamus

Question 6

Estrogens (Conjugated) with Medroxyprogesterone Acetate

Answer 6

Estrogen and Progestin combination
Birth control/osteoporosis
supress the LH and FSH resulting in the inhibition of ovulation

Question 7

Fesoterodine Fumarate

Answer 7

Anticholinergic agent
Overactive bladder/Urinary incontinence
Competitive muscarinic receptor antagonist, block Ach in the bladder. Reduces smooth muslce tone in the bladder.

Question 8

Glyburide

Answer 8

Antidiabetic Agent, Sulfonylurea
DM
stimulates insulin synthesis and release for beta cells in the pancreatic islets, improve b/n insulin and its receptors

Question 9

Ibandronate Sodium

Answer 9

Bisphosphonate derivative
osteoporosis
inhibits osteoclast-mediated bone reasoprtion

Question 10

Insulin

Answer 10

Insulin
T1DM/T2DM
acts like insulin, promotes transport of monosacchrides, transformation of a.a. into proteins, decreases formation of TGs

Question 11

Insulin Detemir

Answer 11

Insulin, Long-acting
DM
acts like insulin, promotes transport of monosacchrides, transformation of a.a. into proteins, decreases formation of TGs

Question 12

Levonorgestrel with Ethinyl Estradiol (monophasic)

Answer 12

Contraceptive
Birth control
Supresses LH and FSH results in the inhibition of ovulation

Question 13

Liraglutide (rDNA origin)

Answer 13

Antidiabetic agent, glucagon-like peptide-1 (GLP-1) receptor agonist
DM
GLP-1 receptor agonist, increase intracellular cAMP -> releases insulin from pancreatic beta cells

Question 14

Medroxyprogesterone Acetate (oral)

Answer 14

Contraceptive
Birth control
Progestins increase the synthesis fo RNA by interactive w/ chromatin cuasing the transformation of porliferative endometrium into secretory endometrium

Question 15

Norethindrone with Ethinyl Estradiol (1/35)

Answer 15

Contraceptive
Birth control
Supresses LH and FSH results in the inhibition of ovulation, thickens cervical mucous and alters endometrium

Question 16

Norethindrone, Ethinyl Estradiol, Ferrous Fumarate

Answer 16

Contraceptive
Birth control
Supresses LH and FSH results in the inhibition of ovulation, thickens cervical mucous and alters endometrium

Question 17

Norgestimate and Ethinyl Estradiol

Answer 17

Contraceptive
Birth control
Supresses LH and FSH results in the inhibition of ovulation, thickens cervical mucous and alters endometrium

Question 18

Norgestrel with Ethinyl Estradiol

Answer 18

Contraceptive
Birth control
Supresses LH and FSH results in the inhibition of ovulation, thickens cervical mucous and alters endometrium

Question 19

Pioglitazone Hydrochloride

Answer 19

Antidiabetic Agent, thiazolidinedione
DM
binds to peroxisome proliferator-activated receptor-gamma (PPAR) that regulates the transcription of a number of insuline responsive genes critical for the control of glucose and lipid metabolism

Question 20

Raloxifene Hydrochloride

Answer 20

Selective estrogen receptor modulator (SERM)
osteoporosis
selective estrogen receptor modulator, decreases bone resorption

Question 21

Saxagliptin

Answer 21

Antidiabetic agent, dipeptidyl peptidase IV (DPP-IV) inhibitor
T2DM
inhibits the dipeptidyl peptidase-4 (DDP-4) enzyme, deactivates the GLP-1 and GIP…increasing insulin synthesis and release from pancreatic beta cells

Question 22

Sildenafil Citrate

Answer 22

Phosphodiesterase-5 enzyme inhibitor
ED
inhibits PDE5, stops degredation of cGMP, increased levels of cGMP allow for inflow of blood

Question 23

Sitagliptin Phosphate and Metformin Hydrochloride

Answer 23

Antidiabetic agent, biguanide and dipeptidyl peptidase IV inhibitor (DPP-IV)
DM

Question 24

Solifenacin Succinate

Answer 24

Anticholinerfic agent
Overactive bladder/Urinary incontinence
Competitive muscarinic receptor antagonist, block Ach in the bladder. Reduces smooth muslce tone in the bladder.

Question 25

Tadalafil

Answer 25

Phosphodiesterase-5 enzyme inhibitor
ED
inhibits PDE5, stops degredation of cGMP, increased levels of cGMP allow for inflow of blood

Question 26

Terazosin Hydrochloride

Answer 26

Alpha-1 blocker
HTN, BPH
decreases TPR by competitively blocking alpha-1-adrenoreceptors, dilates arterioles and veins

Question 27

Testosterone Gel (topical)

Answer 27

Androgen
hormone replacement
acts like testoserone in the body

Question 28

Tolterodine Tartrate

Answer 28

Anticholinergic agent
Overactive bladder/Urinary incontinence
Competitive muscarinic receptor antagonist, block Ach in the bladder. Reduces smooth muslce tone in the bladder.