Drug quiz 5 errthing Flashcards
Brand: Subutex
Generic: buprenophine
Class: Analgesic, opioid Dose: 16 mg ROA: SL Indication: Opiod dependence MOA: partial opiod agonist/antagonist. Partial agonist at the mu-opiod receptor and an antagonist at the kappa-opiod receptor.
Brand: Fioricet
Generic: butalbital, acetaminophen and caffeine
Class: Barbiturate
Dose: 1-2 Tab Q4H (don’t exceed 6 tab/day)
ROA: PO
Indication: tension headache
MOA: acetaminophen inhibits PG syn and peripheral, butalbital - sensory cortex depression via inhib of conduction in the reticular formation, caffeine - CNS stimulation by inhib of phosphodiesterase which inc the accumulation of cAMP
Brand: Colcrys
Generic: colchicine
Class: Antigout agent Dose: 1 - 2 Tabs Q1-2H PRN ROA: PO indication: gout MOA: binds to microtubular protein which leads to inhibition of the migration of granulocytes into the inflammed area.
Brand: Dexilant
Generic: dexlansoprazole
Class: Proton pump inhibitor Dose: 30 mg QD ROA: PO indication: GERD, heartburn MOA: inhibits the H+/K+ ATPase enz system at the secretory surface of the gastric parietal cell
Brand: Voltaren Gel
Generic: Diclofenac Sodium (topical)
Class: NSAID
Dose: apply 2 g upper extremity/ 4 g lower extremity
ROA: topical
indication: relief joint pain
MOA: exact MOA is unknown, possible inhibition of COX
Brand: Lomotil
Generic: diphenoxylate HCl with Atropine Sulfate
Class: Antidiarrheal Dose: 2 tabs or 2 tsp up to QID indication: diarrhea ROA: PO MOA: binds to intestinal opiate receptors decreasing peristalsis and affecting water and electrolyte movement
Brand: Dilaudid
Generic: hydromorphone HCl
Class: Analgesic, opioid Dose: 2 - 4 mg Q4-6H ROA: PO indication: pain mgmt MOA: pure opiod agonist
Brand: Levsin, Levbid
Generic: hyoscyamine Sulfate
Class: Anticholinergic agent
Dose: 0.125-0.25 mg Q4H PRN
ROA: PO
indication: GI antispasmatic (peptic ulcer, IBS, etc
MOA: inhibits the muscarinic action of acetylcholie on the smooth muscle
Brand: Indocin
Generic: indomethacin
Class: NSAID) Dose: 25 - 50 mg BID to TID (200 mg) ROA: PO indication: severe OA or RA pain MOA: inhibition of COX resulting in a decreased biosynthesis or prostaglandins
Brand: Kristalose, Enulose
Generic: lactulose
Class: Laxative, osmotic Dose: 10 - 20 gm per day ROA: PO indication: constipation MOA: broken down into lactic acid, increases osmotic pressure and a pH elevation in the colon
Brand: Lidoderm
Generic: lidocaine (Transdermal)
Class: Analgesic, topical
Dose: apply patch to painful area for 12 hrs w/in a 24 hr period
ROA: topical
indication: post-herpetic neuralgia
MOA: neuronal mbr-stabilizing properties by combining w/ fast sodium channels during their inactive state to inhibit repolarization
Brand: Amitiza
Generic: lubiprostone
Class: Gastrointestinal agent Dose: 8 mcg BID w/ food and water ROA: PO indication: IBS MOA: chloride channel activator which increases chloride-rich intestinal fluid secretion w/o altering serum sodium or potassium; activated CIC-2 in the apical mbr of the intestine
Brand: Pentasa, Asacol HD, Lialda, Delzicol
Generic: mesalamine (oral)
Class: 5-aminosalicylic acid derivative Dose: 2.4-4.8 g QD ROA: PO indication: ulcerative colitis MOA: blocks COX and inhibits PG formation which decreased the formation of arachiodonic acid metabolites
Brand: Skelaxin
Generic: metaxalone
Class: Skeletal muscle relaxant Dose: 800 mg TID/QID ROA: PO indication: muscle relaxant MOA: CNS depressant effects, no direct action on the muscle
Brand: Relafen
Generic: nabumetone
Class: NSAID
Dose: maintenance 500 - 2000 mg QD (1 or 2 doses)
ROA: PO
indication: NSAID
MOA: halts prostaglandin synthesis, antiinflammatory, analgesic, and antipyretic properties
Brand: Anaprox
Generic: naproxen sodium
Class: NSAID Dose: 550 mg initi. then 275 mg Q6-8H ROA: PO indication: NSAID MOA: inhibits COX resulting in decreased biosynthesis of PG
Brand: Norflex
Generic: orphenadrine citrate
Class: Skeletal muscle relaxant Dose: 100 mg BID ROA: PO indication: muslce relaxant MOA: centrally acting antimuscarinic agent w/ analgesic and anticholinergic properties
Brand: Pyridium
Generic: phenazopyridine hydrochloride
Class: Analgesic, urinary Dose: 200 mg TID PC (after meals) ROA: PO indication: urinary tract MOA: excreted in the urine where it exerts a topical analgesic effect on the urinary tract mucosa, exact MOA unknown
Brand: Feldene
Generic: piroxicam
Class: NSAID Dose: 20 mg QD in sing/div doses ROA: PO indication: OA or RA pain MOA: inhibition of COX resulting in a decreased biosynthesis or prostaglandins
Brand: Mexalt
Generic: rizatriptan benzoate
Class: Antimigraine, serotonin 5-HT 1 receptor agonist
Dose: 5-10 mg at 1st sign of migraine
ROA: PO
indication: migraine
MOA: selective agonist for vascular 5-hydroxytryptamine 1 receptor and 5-HT1 receptor, vasoconstriction
Brand: Carafate
Generic: sucralfate
Class: Gastrointestinal agent Dose: 1 gm QID on empty stomach ROA: PO indication: duodenal ulcer MOA: formation of an ulcer-adherent complex that covers the ulcer site and protects it against further damage by neutralizing gastric acid
Brand: Ultracet
Generic: tramadol hydrochloride with acetaminophen
Class: Analgesic Dose: 2 tab Q4-6H prn for pain ROA: PO indication: pain mgmt MOA: binding to m-opiod receptors and inhibition of reuptake of NE an dserotonin and acetaminophen inhibits PG synthesisin the CNS
