DPR - Prelims

Question 1

This receptor causes vasoconstriction in the walls of blood vessels, mydriasis, urinary retention and ejaculation

Answer 1

a-1 receptor

Question 2

This receptor is a pre-synaptic neuron that inhibits the release of norepinephrine and serbes a mechanism of negative feedback control

Answer 2

a-2 receptor

Question 3

2 types of a blockers

Answer 3

non-selective and seletive

Question 4

An irreversible, non-competitive antagonist that is used for pheochromocytoma

Answer 4

Phenoxybenzamine

Question 5

A reversible, competitive antagonist for hypertensive crisis

Answer 5

Phentolamine

Question 6

Non-selective a blockers

Answer 6

Phenoxybenzamine and phentolamine

Question 7

Side effects of non-selective a blockers

Answer 7

vasodilation, orthostatic hypotension, sexual dysfunction and nasal congestion

Question 8

effects of inhibiting a-2 receptors

Answer 8

leading to uncontrolled release of catecholamines

Question 9

Selective a-1 blockers

Answer 9

Prazosin
Doxazosin
Terazosin
Tamsulosin

Question 10

A less-effective on a-1 receptor that is used to relieve urinary retention and for intraoperative floppy iris syndrome

Answer 10

Tamsulosin

Question 11

Selective a-1 blockers effective in lowering blood pressure

Answer 11

Prazosin
Doxazosin
Terazosin

Question 12

Side Effects of Selective a blockers

Answer 12

risk of hypotenstion, tachycardia and arrhythmia