DPP4 Inhibitors Flashcards

prevent the enzyme DPP4 from breaking down incretin hormones GLP1 and GIP

1
Q

What medications are DPP4 inhibitors

A
  • Sitagliptin (Januvia)*
  • Linagliptin (Tradjenta)*
  • Saxagliptin (Onglyza)
  • Alogliptin (Nesina)
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2
Q

What is the only DPP4 inhibitor that does not require renal dose adjustments?*

A

Linagliptin (Tradjenta)

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3
Q

(Linagliptin) Tradjenta dose

A

5 mg daily

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4
Q

Sitagliptin (Januvia) dose
- renal dose

A

100 mg daily
- eGFR 30-45: 50 mg daily
- eGFR < 30: 25 mg daily

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5
Q
A
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