DPP4 Inhibitors Flashcards
prevent the enzyme DPP4 from breaking down incretin hormones GLP1 and GIP
1
Q
What medications are DPP4 inhibitors
A
- Sitagliptin (Januvia)*
- Linagliptin (Tradjenta)*
- Saxagliptin (Onglyza)
- Alogliptin (Nesina)
2
Q
What is the only DPP4 inhibitor that does not require renal dose adjustments?*
A
Linagliptin (Tradjenta)
3
Q
(Linagliptin) Tradjenta dose
A
5 mg daily
4
Q
Sitagliptin (Januvia) dose
- renal dose
A
100 mg daily
- eGFR 30-45: 50 mg daily
- eGFR < 30: 25 mg daily
5
Q
A