DPLD/ ILD

Question 1

DPLD

Answer 1

Diffuse parenchymal lung disease = Same as ILD

Question 2

DPLD

Answer 2

results in restrictive lung disease that does not move oxygen well

Question 3

S&S

Answer 3

Chronic insidious onset
Hypoxemia
Dry cough
Dry crackles
Restrictive pattern

Question 4

Diagnosis

Answer 4

X-ray --> generally reticular nodular pattern (ground glass)
PFT --> restrictive pattern (FEV1/FVC will be normal or increased >0.8)
Decreased diffusion (DLCO)

Question 5

Tx

Answer 5

Anti-inflammatory
Steroids***
DMARDs
Biologics

Question 6

Idiopathic

Answer 6

Tx with steroids
if acute: called acute interstitial pneumonitis
if chronic: idiopathic pulmonary fibrosis (drug-induced: bleomycin and amiodarone; or due to radiation)

Question 7

Rheumatologic disease can also cause pulmonary fibrosis

Answer 7

SLE
RA
SS

Question 8

Primary lung disease

Answer 8

Sarcoidosis

Question 9

Exposure lung disease

Answer 9

Asbestosis
Hypersensitivity
Pneumoconiosis (silicosis, berylliosis, coal)

Question 10

Sarcoidosis

Answer 10

Autoimmune; affects black women

Hilar lymphadenopathy, asymptomatic

Insidious hypoxemia, heart block, Bell’s Palsy, and erythema nodosum

Question 11

Sarcoidosis- diagnosis

Answer 11

CXR: bilateral hilar LA
High res: ground glass
PFTs: restrictive
Biopsy: non-caseating granulomas

Question 12

Tx

Answer 12

steroids

Question 13

to identify cardiac involvement

Answer 13

Get cardiac MRI

Question 14

Asbestosis

Answer 14

Path: increases risk of cancer

Exposure: shipyards and construction (after 30+ years of exposure)

Pleural plaques on X-ray

Question 15

Asbestosis- diagnosis

Answer 15

imaging

biopsy: barbell bodies

Question 16

Tx

Answer 16

stop smoking if they are

Question 17

Exposure

Answer 17

Hypersensitivity pneumonitis (HP): bird fanciers; antigen-mediated (takes 24-48 hrs to onset and 24-48 hrs for relief after exposure); tx: remove environmental exposure; DOES NOT NEED STEROIDS

Silicosis: sandblasting, rock quarry (looks like TB- affects upper lobes)

Berylliosis: aeronautics industry, electronics

Coal: coal miner (Caplan syndrome: arthralgias, pulmonary fibrosis)