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Endo/Repro: Week 5 > Downing: Placental Histology > Flashcards

Downing: Placental Histology Flashcards

1
Q

required for for endometrial invasion by the placenta

A

secretory phase

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2
Q

trophoblast proliferation (lacunar formation) >
uterine epithelium regneration>
decidual rxn

A

Endometrial invasion of the placenta

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3
Q

Components of the chorionic villi

A

extraembryonic mesoderm
cytotrophoblast
syncytiotrophoblast

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4
Q

1 villi

A

trophoblast only, no extraembryonic mesoderm yet

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5
Q

2 villi

A

mesodermal ingrowths into villous core

branding occurs

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6
Q

villi w/ cytotrophoblastic shell that invade through the syncytiotrophoblast and have direct contact w/ decidual cells

A

anchoring villi

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7
Q

villus that have differentiation of blood vessels in villus core and eventual anastamosis of villar blood vessels w/ fetal circulation

A

3 villus

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8
Q

where is the decidua basalis formed

A

between conceptus and myometrium

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9
Q

this constitutes the MATERNAL portion of hte placenta and is the site of decidual rxna nd most extensive villar invasion

A

decidua basalis

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10
Q

between the conceptus and uterine lumen

A

decidua capsularis

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11
Q

decidua parietalis

A

remainder of endometrium

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12
Q

Cotyledons

A

placenta divided into 15-30 lobules by septae from decidua basalis (contain 3 villi branches)

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13
Q

Fetal placenta circulation

A 
umbilical a>
chorionic a>
villar capillaries>
chorionic veins>
umbilical veins
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14
Q

Maternal placental circulation

A

spiral arteries>
intervilous space>
endometrial veins

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15
Q

How often is blood in intervillous spaces replenished?

A

3-4x/min

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16
Q

first trimester placental barrier

A 
syncytiotrophoblast
cytotrophoblast
basal lamina of trophoblast
fetal CT
basal lamina of fetal capillaries
fetal endothelium
17
Q

What happens to the first trimester barrier after 20 weeks?

A

cytotrophoblast disappears and CT thins and barrier is reduced to:

syncytiotrophoblast
basal laminae
fetal capillaries

18
Q

what is transferred in the placenta

A 
gases
nutrients
hormones
IgG
fetal RBC (RH incompat)
urea
drugs
viruses (NO bacteria)
19
Q

origin of most placental hormones

A

syncytiotrophoblast

20
Q

LH like glyucoprotein that MAINTAINS the CL and measure ment is used to detect pregnancy

A

hCG

21
Q

related to HGH, stimualtes general growth and is lactogenic

A

Human placental lactogen

22
Q

synthesized by decidual cells

A

PRL
PG
Relaxin

23
Q

helps soften cervix and pelvic ligaments

A

relaxin

Endo/Repro: Week 5 (6 decks)

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