Dose Constraints Flashcards

1
Q

CNS standard fractionation

Lens

A

5-7 Gy

MPD

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2
Q

CNS standard fractionation

Retina

A

45 Gy

MPD

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3
Q

CNS standard fractionation

Optic Nerve

A

54 Gy

MPD

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4
Q

CNS standard fractionation

Chiasm

A

54 Gy

MPD

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5
Q

CNS standard fractionation

Brainstem

A

55-60 Gy (adults)
50.4 Gy (peds)
MPD

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6
Q

CNS standard fractionation

Cochlea

A

Mean <35 Gy

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7
Q

CNS standard fractionation

Spinal Cord

A

45 Gy

MPD

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8
Q
CNS SRS (1 fx)
Lens
A

1 Gy

MPD

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9
Q
CNS SRS (1 fx)
Optic Nerve
A

8 Gy

MPD

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10
Q
CNS SRS (1 fx)
Chiasm
A

8 Gy

MPD

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11
Q
CNS SRS (1 fx)
Brainstem
A
12 Gy (MPD)
Limit healthy brainstem to 10-12 Gy to 1 cc
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12
Q
CNS SRS (1 fx)
Cochlea
A

Mean: <4 Gy
MPD: <12 Gy

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13
Q
CNS SRS (1 fx)
Spinal Cord
A

14 Gy MPD

<12 Gy if prior RT

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14
Q
CNS SRS (5 fx Brain or Spine)
Optic Nerve
A

23 Gy

MPD

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15
Q
CNS SRS (5 fx Brain or Spine)
Chiasm
A

23 Gy

MPD

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16
Q
CNS SRS (5 fx Brain or Spine)
Brainstem
A

30 Gy

MPD

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17
Q
CNS SRS (5 fx Brain or Spine)
Spinal Cord
A

30 Gy MPD

<10 Gy if prior RT

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18
Q

Reportable event i ftotal course dose delivered exceeds

A

20%

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19
Q

Reportable event if daily total dose delivered exceeds prescribed dose by

A

50%

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20
Q

Bilateral mean kidney dose to keep clinically relevant renal dysfunction <5%

A

15-18 Gy

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21
Q

V50 for rectum to keep grade 3+ late rectal tox <10%

A

50%

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22
Q

V60 for rectum to keep grade 3+ late rectal tox <10%

A

35%

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23
Q

V65 for rectum to keep grade 3+ late rectal tox <10%

A

25%

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24
Q

V70 for rectum to keep grade 3+ late rectal tox <10%

A

20%

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25
V75 for rectum to keep grade 3+ late rectal tox <10%
15%
26
Whole organ brainstem dose to keep necrosis <5%
54 Gy
27
D1-10cc dose to brainstem to keep necrosis <5%
59 Gy
28
Risk of optic neuropathy with Dmax 55 Gy
<3%
29
Risk of optic neuropathy with Dmax 55-60
3-7%
30
Risk of optic neuropathy with Dmax >60
7-20%
31
V15 goal to duodenum for pancreas SBRT
<9 cc
32
V20 goal to duodenum for pancreas SBRT
<3 cc
33
Bladder V65
<50%
34
Bladder V70
<35%
35
Bladder V75
<25%
36
Bladder V80
<15%
37
Mean dose to pharyngeal constrictors to keep risk of aspiration <20%
50 Gy to full organ
38
Risk of serviceable hearing loss after SRS with dose <14 Gy to cochlea
<25%
39
Conventional fractionation dose contraint to cochlea
mean dose <45 Gy
40
Mean dose of 45 gy to cochlea corresponds to what risk of hearing loss
<30%
41
SRS max dose to cochlea
<8-9 Gy
42
Whole organ constraint to brainstem
54 Gy
43
Constraint for hypoglossal nerve
D1cc < 74 Gy
44
Cumulative dose to AICD should not be above
2-5 Gy
45
Risk of RT myelitis with Dmax 50
0.2%
46
What section of cord does QUANTEC refer to
full cross section
47
Risk of RT myelitis with Dmax 60
6%
48
Risk of RT myelitis with Dmax 69
50%
49
3 fraction SBRT spinal cord constraint
18-20 Gy
50
1 fraction SRS spinal cord constraint
13 Gy
51
Dmax of X to whole brain has <3% risk of radionecrosis
60 Gy
52
What dose has 5% risk of brain necrosis
72 Gy
53
What dose has 10% risk of brain necrosis
90 Gy
54
For HA-WBRT, what is the dose constraint for hippocampi
D100% < 9 Gy
55
For HA-WBRT, what is the dose Dmax constraint for hippocampi
<16 Gy
56
Mean liver dose allowed for 3 fx SBRT
13-15 Gy
57
For liver SBRT >700 cc needs to have < X Gy
15 Gy
58
SRS brain constraint
V12 < 5-10 cc
59
SRS V12 corresponds to
<20% risk of radionecrosis
60
Esophagus mean should be
<34 Gy
61
Mean dose to unilateral parotid
<20 Gy - long term risk of salivary function <25%
62
Mean dose to bilateral parotid
<25 Gy - long term risk of salivary function <25%
63
V20 goal
<30%
64
What does V20 < 30% correspond to in terms of pneumonitis risk
<20%
65
SRS Dmax constraint for brainstem
12.5 [risk of CN injury <5%]
66
Risk of gastric ulceration of whole organ gets 45 Gy
7%
67
If mean dose to bilateral parotids is 39 Gy, rate of reducing parotid function <25% of baseline is
50%