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RO Clinical Boards > Dose Constraints > Flashcards

Dose Constraints Flashcards

1
Q

CNS standard fractionation

Lens

A

5-7 Gy

MPD

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2
Q

CNS standard fractionation

Retina

A

45 Gy

MPD

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3
Q

CNS standard fractionation

Optic Nerve

A

54 Gy

MPD

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4
Q

CNS standard fractionation

Chiasm

A

54 Gy

MPD

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5
Q

CNS standard fractionation

Brainstem

A

55-60 Gy (adults)
50.4 Gy (peds)
MPD

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6
Q

CNS standard fractionation

Cochlea

A

Mean <35 Gy

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7
Q

CNS standard fractionation

Spinal Cord

A

45 Gy

MPD

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8
Q 
CNS SRS (1 fx)
Lens
A

1 Gy

MPD

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9
Q 
CNS SRS (1 fx)
Optic Nerve
A

8 Gy

MPD

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10
Q 
CNS SRS (1 fx)
Chiasm
A

8 Gy

MPD

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11
Q 
CNS SRS (1 fx)
Brainstem
A 
12 Gy (MPD)
Limit healthy brainstem to 10-12 Gy to 1 cc
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12
Q 
CNS SRS (1 fx)
Cochlea
A

Mean: <4 Gy
MPD: <12 Gy

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13
Q 
CNS SRS (1 fx)
Spinal Cord
A

14 Gy MPD

<12 Gy if prior RT

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14
Q 
CNS SRS (5 fx Brain or Spine)
Optic Nerve
A

23 Gy

MPD

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15
Q 
CNS SRS (5 fx Brain or Spine)
Chiasm
A

23 Gy

MPD

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16
Q 
CNS SRS (5 fx Brain or Spine)
Brainstem
A

30 Gy

MPD

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17
Q 
CNS SRS (5 fx Brain or Spine)
Spinal Cord
A

30 Gy MPD

<10 Gy if prior RT

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18
Q

Reportable event i ftotal course dose delivered exceeds

A

20%

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19
Q

Reportable event if daily total dose delivered exceeds prescribed dose by

A

50%

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20
Q

Bilateral mean kidney dose to keep clinically relevant renal dysfunction <5%

A

15-18 Gy

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21
Q

V50 for rectum to keep grade 3+ late rectal tox <10%

A

50%

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22
Q

V60 for rectum to keep grade 3+ late rectal tox <10%

A

35%

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23
Q

V65 for rectum to keep grade 3+ late rectal tox <10%

A

25%

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24
Q

V70 for rectum to keep grade 3+ late rectal tox <10%

A

20%

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25
Q

V75 for rectum to keep grade 3+ late rectal tox <10%

A

15%

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26
Q

Whole organ brainstem dose to keep necrosis <5%

A

54 Gy

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27
Q

D1-10cc dose to brainstem to keep necrosis <5%

A

59 Gy

28
Q

Risk of optic neuropathy with Dmax 55 Gy

A

<3%

29
Q

Risk of optic neuropathy with Dmax 55-60

A

3-7%

30
Q

Risk of optic neuropathy with Dmax >60

A

7-20%

31
Q

V15 goal to duodenum for pancreas SBRT

A

<9 cc

32
Q

V20 goal to duodenum for pancreas SBRT

A

<3 cc

33
Q

Bladder V65

A

<50%

34
Q

Bladder V70

A

<35%

35
Q

Bladder V75

A

<25%

36
Q

Bladder V80

A

<15%

37
Q

Mean dose to pharyngeal constrictors to keep risk of aspiration <20%

A

50 Gy to full organ

38
Q

Risk of serviceable hearing loss after SRS with dose <14 Gy to cochlea

A

<25%

39
Q

Conventional fractionation dose contraint to cochlea

A

mean dose <45 Gy

40
Q

Mean dose of 45 gy to cochlea corresponds to what risk of hearing loss

A

<30%

41
Q

SRS max dose to cochlea

A

<8-9 Gy

42
Q

Whole organ constraint to brainstem

A

54 Gy

43
Q

Constraint for hypoglossal nerve

A

D1cc < 74 Gy

44
Q

Cumulative dose to AICD should not be above

A

2-5 Gy

45
Q

Risk of RT myelitis with Dmax 50

A

0.2%

46
Q

What section of cord does QUANTEC refer to

A

full cross section

47
Q

Risk of RT myelitis with Dmax 60

A

6%

48
Q

Risk of RT myelitis with Dmax 69

A

50%

49
Q

3 fraction SBRT spinal cord constraint

A

18-20 Gy

50
Q

1 fraction SRS spinal cord constraint

A

13 Gy

51
Q

Dmax of X to whole brain has <3% risk of radionecrosis

A

60 Gy

52
Q

What dose has 5% risk of brain necrosis

A

72 Gy

53
Q

What dose has 10% risk of brain necrosis

A

90 Gy

54
Q

For HA-WBRT, what is the dose constraint for hippocampi

A

D100% < 9 Gy

55
Q

For HA-WBRT, what is the dose Dmax constraint for hippocampi

A

<16 Gy

56
Q

Mean liver dose allowed for 3 fx SBRT

A

13-15 Gy

57
Q

For liver SBRT >700 cc needs to have < X Gy

A

15 Gy

58
Q

SRS brain constraint

A

V12 < 5-10 cc

59
Q

SRS V12 corresponds to

A

<20% risk of radionecrosis

60
Q

Esophagus mean should be

A

<34 Gy

61
Q

Mean dose to unilateral parotid

A

<20 Gy - long term risk of salivary function <25%

62
Q

Mean dose to bilateral parotid

A

<25 Gy - long term risk of salivary function <25%

63
Q

V20 goal

A

<30%

64
Q

What does V20 < 30% correspond to in terms of pneumonitis risk

A

<20%

65
Q

SRS Dmax constraint for brainstem

A

12.5 [risk of CN injury <5%]

66
Q

Risk of gastric ulceration of whole organ gets 45 Gy

A

7%

67
Q

If mean dose to bilateral parotids is 39 Gy, rate of reducing parotid function <25% of baseline is

A

50%

RO Clinical Boards (13 decks)

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