Dosages: Induction Agents, NMBAs, Reversal, Locals Flashcards
Propofol
Adult - Induction
1.5 - 2.5mg/kg
Propofol
Pediatric - Induction
2-3mg/kg
Propofol
Sedation (MAC)
25-100mcg/kg/min
Propofol
Adult - Maintenance of General Anesthesia
100-300mcg/kg/min
TIVA
Propofol Pediatric (Book) - Maintenance of General Anesthesia
60-250mcg/kg/min
TIVA
Propofol Pediatric (Reality) - Maintenance of General Anesthesia
200-400mcg/kg/min
TIVA
Propofol
PONV
10-15mg
Use Caution
Lidocaine
Analgesia for Propofol
20mg of 2% Lidocaine
Mix just prior to injection
Etomidate
Induction Dose
0.2-0.4mg/kg
Ketamine
Induction (IV)
1-2mg/kg
IV Bolus
Ketamine
Induction (IM)
4-8mg/kg
IM
Ketamine
Analgesia
0.2-0.5mg/kg
IV
Succinylcholine (SCh)
Intubating Dose
1-1.5mg/kg
Succinylcholine (SCh)
Rapid Sequence Dose
1.5mg/kg
Succinylcholine (SCh)
Time Profile
RAPID Onset: 30-60 second
Short Duration: 5-10minutes
Short DMR
Pancuronium
Intubating Dose
0.1mg/kg
Pancuronium
Time Profile
SLOW Onset: 3-5 minutes
LONG Duration: 60-90 minutes
Longest Acting NDMB
“Priming Dose”
10% of ED95
Used to INCREASE onset of NDMB for Intubation
“Defasciculating Dose”
10% of ED95 of a NDMB
Used to DECREASE Fasiculations seen with SCh
Will require larger dose of SCh for intubation
Vecuronium
Intubating Dose
0.1mg/kg
Vecuronium
Time Profile
Onset: 3-5 minutes
Duration: 20-35 minutes
Intermediate Acting / Aminosteroid
Rocuronium
Intubating Dose
0.6mg/kg
Rocuronium
Rapid Sequence Dose
1.2mg/kg
Rocuronium
Normal Time Profile
Onset: 1-2 minutes
Duration: 20-35 minutes
Intermediate NDMR / Aminosteroid
Rocuronium
RSI Time Profile
RAPID Onset: 30-45 seconds
PROLONGED Duration: 60-90 minutes
Rapid due to DOUBLING Dose
Atracurium
Intubating Dose
0.5mg/kg
Atracurium
Time Profile
Onset: 3-5 minutes
Duration: 20-35 minutes
Intermediate NDMR / Bezylisoquinolinium
Cisatracurium
Intubating Dose
0.2mg/kg
Cisatracurium
Time Profile
Onset: 3-5 minutes
Duration: 20-35 minutes
Intermediate NDMR / Bezylisoquinolinium
Neostigmine
Dose
0.07 mg/kg
(Max Dose 5mg)
Anticholinesterase
Pyridostigmine
Dose
0.35mg/kg
(Max Dose 20mg)
Anticholinesterase
Edrophonium
Dose
1mg/kg
(Fastest in Class, Can use Atropine or Glycopyrrolate)
Onset: 1-2 minutes
Anticholinesterase
Physostigmine
Dose
0.03mg/kg
(Crosses BBB, May Cause Central Cholinergic Crisis)
Doesn’t require antimuscarinic/anticholinergic
Anticholinesterase
Physostigmine
Central ANTI-Cholinergic Treatment
15-60mcg/kg
Physostigmine crosses BBB
Glycopyrrolate
Dose
0.01-0.012mcg/kg
w/ Neostigmine and Pyridostigmine
Neostigmine + Glycopyrrolate
Dosing
Neo 1mg + Glyco 0.2mg Neo 2mg + Glyco 0.4mg Neo 3mg + Glyco 0.6mg Neo 4mg + Glyco 0.7mg Neo 5mg + Glyco 0.8mg (Neostigmine MAX Dose 5mg)
Chloroprocaine
Single Dose
800mg
Fastest Ester
Chloroprocaine
Single w/ Epi
1000mg
w/ Epi
Chloroprocine
Weight Based
9mg/kg
weight Based
Chloroprocaine
Weight Based w/ Epi
12mg/kg
w/ Epi weight Based
Procaine
Single Dose
400mg
Procaine
Single w/ Epi
600mg
w/ Epi
Procaine
Weight Based
7mg/kg
weight based
Procaine
Weight w/ Epi
12mg/kg
w/ Epi weight based
Tetracaine
Single Dose
100mg
(slowest ester)
No Weight Based
Tetracaine
Single w/ Epi
200mg
(w/ Epi)
No Weight Based
Prilocaine
Single Dose
500mg
No Epi, No Weight Dosing
Lidocaine
Single Dose
300mg
Lidocaine
Single w/ Epi
500mg
w/ Epi
Lidocaine
Weight Based
5mg/kg
weight based
Lidocaine
Weight w/ Epi
7mg/kg
w/ Epi weight based
Mepivicaine
Single Dose
300mg
Mepivicaine
Single w/ Epi
500mg
w/ Epi
Mepivicaine
Weight Based
5mg/kg
(weight based)
NO Epi Weight Based
Ropivicaine
Single Dose
300mg
no single w/ Epi, or Weight Based
Bupivacaine
Single Dose
175mg
Bupivacaine
Single w/ Epi
225mg
w/ Epi
Bupivacaine
Weight Based
2.5mg/kg
weight based
Bupivacaine
Weight w/ Epi
3mg/kg
weight w/ Epi