Dosages

Question 1

Thiopental

Answer 1

Induction 2.5-5mg/kg

Question 2

Methohexital

Answer 2

ECT ↓ seizure threshold
Induction 1-2mg/kg
Infusion 50-150mcg/kg/min

Question 3

Midazolam (Versed)

Answer 3

IV 0.02-0.04mg/kg
PO 0.4-0.8mg/kg
Sedation post-op 0.5-4mg load
Infusion 1-7mg/hr

Question 4

Diazepam (Valium)

Answer 4

Induction 0.5-1mg/kg

Anticonvulsant 0.1mg/kg

Question 5

Lorazepam (Ativan)

Answer 5

IV 1-4mg

PO 50mcg/kg

Question 6

Flumazenil

Answer 6

Initial 0.2mg
0.1mg Q1min
0.5-1mg to reverse effects
> 5mg no response another issue

Question 7

Propofol

Answer 7

Induction 1.5-2.5mg/kg
MAC sedation 25-100mcg/kg/min (1.5-6mg/kg)
Anesthesia maintenance TIVA 100-300mcg/kg/min
Antiemetic 10-15mg then 10mcg/kg/min
Antipruritic 10mg
Anticonvulsant 1mg/kg

Question 8

Etomidate

Answer 8

Induction 0.2-0.4mg/kg

Question 9

Ketamine

Answer 9

Induction 1-2.5mgkg IV
IM 4-8mg/kg
PO 10mg/kg 
Analgesic 0.2-0.5mg/kg (somatic > visceral)
0.5-1mg/kg prior to surgical incision

Question 10

Dexmedetomidine (Precedex)

Answer 10

TIVA 0.5-1mcg/kg bolus over 15min
Infusion 0.2-0.7mcg/kg/hr
0.5-2mcg/kg
Bolus 4mcg up to 16-20mcg

Question 11

Scopolamine

Answer 11

IV/IM 0.3-0.5mg

Antiemetic 1.5mg patch

Question 12

Physostigmine

Answer 12

Reversal 15-60mcg/kg IV

Question 13

Morphine

Answer 13

IV 0.1-0.2mg/kg

IM 4mg

Question 14

Codeine

Answer 14

PO 15mg
60mg = 650mg ASA
IM 120mg = 10mg Morphine

Question 15

Meperidine

Answer 15

Anti-shivering

12.5mg

Question 16

Fentanyl

Answer 16

75-125x more potent than Morphine
Block sympathetic stim 1-3mcg/kg (prior to anesthesia induction)
Analgesia 1-3mcg/kg
Surgical as sole anesthetic 50-150mcg/kg
Peds PO 15-20mcg/kg (pre-op sedation)

Question 17

Sufentanil

Answer 17

5-10x more potent than Fentanyl
Analgesia 0.1-0.4mcg/kg
*Chest wall rigidity

Question 18

Alfentanil

Answer 18

Less potent than Fentanyl
Blunt stimulation 15mcg/kg (laryngoscopy)
Catecholamine response 30mcg/kg (noxious stim)
Induction 150-300mcg/kg (produces unconscious)
Combination w/ inhalation anesthetic 15-150mcg/kg/hr

Question 19

Remifentanil

Answer 19

Induction 0.25-1 or 1-3mcg/kg bolus prior to induction agent
Analgesia TIVA 0.05-0.2 or 0.1-0.3mcg/kg/min
Sedation 0.05-0.1mcg/kg/min in combination w/ 2mg Midazolam

Question 20

Hydromorphone (Dilaudid)

Answer 20

Acute post-operative pain
5x more potent than Morphine
0.5-1mg

Question 21

Methadone

Answer 21

IV 20mg
Substitute Morphine 1/4 dosage
Post-op analgesia >24hrs

Question 22

Tramadol

Answer 22

Less potent than Morphine

Question 23

Nalbuphine

Answer 23

10mg IV/IM Q3-6H
Maximum single dose 20mg
Induction 0.3-3mg/kg
Maintenance 0.25-0.5mg/kg

Question 24

Buprenorphine

Answer 24

Potent analgesic

0.3mg IM = 10mg Morphine

Question 25

Naloxone

Answer 25

IV 1-4mcg/kg | PCA 5mcg/kg/hr fix respiratory depression w/out affecting analgesia

Question 26

Nalmefene

Answer 26

IV 15-25mcg | MAX 1mcg/kg

Question 27

Ketorolac (Toradol)

Answer 27

IV/IM 15mg Q6H | Avoid in renal compromise

Question 28

Celecoxib (Celebrex)

Answer 28

400mg PO pre-op | 200mg BID x5 days post-op

Question 29

Acetaminophen (Tylenol)

Answer 29

PO 325-650mg Q4-6H IV 1,000mg Q6H MAX 4,000mg/24H (2,000mg chronic alcoholics)

Question 30

Gabapentin

Answer 30

Pre-op 1,200mg 1-2hr prior surgery | PO 600mg Q8H x 14 days

Question 31

Lidocaine

Answer 31

Induction 1-1.5mg/kg Bolus 1.5mg/kg Infusion 1-2mg/kg/hr

Question 32

Magnesium Sulfate

Answer 32

Bolus 30-50mg/kg | Infusion 10mg/kg/hr or 1-2G/hr

Question 33

Succinylcholine

Answer 33

Intubating dose 1mg/kg

Question 34

Atracurium

Answer 34

Intubating dose 0.5mg/kg

Question 35

Cisatracurium

Answer 35

Intubating dose 0.1mg/kg

Question 36

Mivacurium

Answer 36

Intubating dose 0.15mg/kg

Question 37

Pancuronium

Answer 37

Intubating dose 0.08mg/kg

Question 38

Vecuronium

Answer 38

Potent & slow onset | Intubating dose 0.1mg/kg

Question 39

Rocuronium

Answer 39

Intubating dose 0.6mg/kg

Question 40

Neostigmine

Answer 40

40-80mcg/kg Maximum dose 6mg NMBD reversal dose based on % block Assess twitches number, strength, and fade

Question 41

Edrophonium

Answer 41

1-1.5mg/kg

Question 42

Glycopyrrolate

Answer 42

5-10mcg/kg 200mcg per 1mg Neostigmine OR 0.4mg per 2mg Neostigmine

Question 43

Atropine

Answer 43

7-10mcg/kg OR 0.01mg/kg

Question 44

Sugammadex

Answer 44

Dose based on TOF TOF >2 = 2mg/kg 1-2 = 4mg/kg 0 = 8-16mg/kg

Question 45

Aprepitant

Answer 45

PO 40-80mg | High risk non-pregnant patients

Question 46

Metoclopramide

Answer 46

0.1-0.25mg/kg Chemotherapy 1-2mg/kg IV slow push

Question 47

Promethazine

Answer 47

12.5-25mg | IM route preferred

Question 48

Dexamethasone

Answer 48

4-10mg | Admin after induction

Question 49

Ondansetron

Answer 49

4mg up to 16mg | Admin 30min prior to surgery end