Dopamine responsive conditions

Question 1

Bromocriptine is used for

Answer 1

for treatment of galactorrhoea and prolactinomas (when it reduces both plasma prolactin concentration + tumour size). It also inhibits the release of growth hormone and is sometimes used in the treatment of acromegaly but somatostatin analogues (such as octreotide) are more effective

Question 2

Cabergoline has

Answer 2

similar side effects to bromocriptine, however patients intolerant of bromocriptine may be able to tolerate cabergoline

Question 3

Quinagolide is used for

Answer 3

hyperprolactinaemia but its side effects differ slightly: Sudden onset of sleep may occur, hypotensive reactions

Question 4

Galactorrhoea

Answer 4

(milky secretion from the breasts, not due to breast-feeding)

Question 5

Prolactinomas

Answer 5

 (a benign tumor (adenoma) of the pituitary gland that produces a
hormone called prolactin)

Question 6

Acromegaly

Answer 6

 (excessive growth hormone GH)