Dopamine Flashcards
Dopamine Class
sympathomimetic, catecholamine, antidysrhythmic, inotropic agent, vasopressor (pregnancy safety not established)
Dopamine Indications
hemodynamically significant hypotension, cardiogenic shock or CHF, distributive shock (anaphylaxis or sepsis), symptomatic bradycardia (refractory to first-line medications)
Dopamine Mechanism
acts directly on the alpha and beta receptors of the sympathetic nervous system to increase inotropy, chronotropy, dromotropy, automaticity, and systemic vascular resistance; causes renal, mesenteric, and coronary artery vasodilation in low doses
Dopamine Side Effects
1. Headache
2. Palpitations
3. Angina
4. Hypertension
5. Nausea
6. Vomiting
7. Tachycardia
8. ventricular irritability
9. Hypotension
10. Vasoconstriction
11. Anxiety
12. Tremulousness
13. Headache
14. Dizziness
15. Dyspnea
Dopamine Contraindications
hypovolemic shock without prior fluid resuscitation, tachydysrhythmias, pheochromocytoma (adrenal gland tumor)
Dopamine Precautions
will increase myocardial oxygen demand and may potentially increase myocardial ischemia and extend an AMI, can worsen tachydysrhythmias and may cause tissue necrosis with IV infiltration
Dopamine interactions
will increase myocardial oxygen demand and may potentially increase myocardial ischemia and extend an AMI, can worsen tachydysrhythmias and may cause tissue necrosis with IV infiltration
Dopamine Routes
IVPB; cannulate large vein to prevent IV infiltration; start second line prior to administration
Dopamine Onset
1–4 minutes
Dopamine Duration
effects cease almost immediately after infusion is discontinued
Dopamine Adult dose - Renal perfusion:
0.5–2 mcg/kg/min
Dopamine Adult dose - inotropic effects:
2–10 mcg/kg/min
Dopamine Adult dose - vasopressor effects:
10–20 mcg/kg/min
Dopamine Pedi Dose - renal perfusion:
0.5–2 mcg/kg/min
Dopamine Pedi Dose - inotropic effects:
2–10 mcg/kg/min
