Donor Screening and Component Preparation

Question 1

What is a blood bank laboratory involved in?

Answer 1

Collection
Storage
Processing
Distribution or human blood products for transfusion

Question 2

Who regulates blood bank laboratories?

Answer 2

AABB

Question 3

Once blood is shipped, what must happen when it arrives to its location?

Answer 3

They must reconfirm the labeled ABO of each RBC containing product

Question 4

Tests are usually requested as a group, referred to as “shorthand notation” what tests are included?

Answer 4

Type and screen
type and cross match
prenatal evaluation
postpartum evaluation
cord blood studies

Question 5

Describe the Armed Service blood program

Answer 5

provides quality blood products to service members whenever and wherever they’re needed. Armed Serviced Whole blood processing laboratories

Question 6

Standard Blood report

Answer 6

current inventory
disposition of blood products in the last 24 hours
blood products required in the next 12-48 hours
amount of blood expiring in the next 7 days
blood required in next 7 days

Question 7

Blood Shipment report

Answer 7

information on the receiver of the blood products
arrival schedule of the shipped blood
type of shipment
shippers address

Question 8

What is an Allogenic donor?

Answer 8

one who donates blood for use by others

Question 9

who manages the criteria for acceptable donors for allogenic and autologous donors

Answer 9

the AABB and FDA

Question 10

Taking these medication can prevent a donor from donating because

Answer 10

piroxicam and asprin because these meds can inhibit platelet function

Question 11

Plasmapheresis

Answer 11

it is the removal and retention of plasma such as antibodies, toxins, or abnormal proteins

Question 12

after completing double rbc pheresis, how long are donors deferred?

Answer 12

16 weeks following a successful completion of the procedure or a total of more than 300ml red cells lost

Question 13

how is membrane technology methodology performed?

Answer 13

uses centrifugal force to separate blood into components based on their difference in density. blood is removed from patient using a large bore needle

Question 14

how do you clean the site of entry when speaking about aseptic techniques

Answer 14

scrub area at least 4cm in all directions from the site for a minimum of 30 seconds

Question 15

mild donor reactions

Answer 15

convulsions

Question 16

moderate donor reactions

Answer 16

loss of consciousness
fall in systolic pressure to 60m hg
to treat this, administer 95% oxygen and 5% carbon dioxide

Question 17

what temperature are rbcs preserved at?

Answer 17

stored in the liquid state between 1 and 6 C

Question 18

what is the longest anticoagulant storage time and how long?

Answer 18

CPDA-1
35 days

Question 19

what are addictive solutions used for?

Answer 19

extends the shelf life of pRBCS to 42 days by adding nutrients and allows for the harvesting of more plasma and platelets from the whole blood unit.

Question 20

What are the types of additive solutions licensed in the united states?

Answer 20

Adsol AS1
Nutricel AS3
Optisol AS5

Question 21

what does Nutricel (AS3) contain

Answer 21

citrate and phosphate

Question 22

what is the additive ratio

Answer 22

450ml bag: 100ml of additive
500ml bag: 110ml of additive

Question 23

Antibody to Hep C and Nucleic Acid test

Answer 23

Enzyme immunoassay used to screen for hep c
confirmed by radioimmunonlot assay (riba)

Question 24

Antibody to human immunovirus 1/2 and nat testing

Answer 24

donors must be screened using eia method.
confirm with western blot and immunofluoresence

Question 25

how many characters are in the isbt number?

Answer 25

14 characters

Question 26

what do red blood cells leukoreduced indicate?

Answer 26

febrile non hemolytic transfusion reactions and transmission of cytomegalovirus

Question 27

what are platelets stored at?

Answer 27

stored at 20-24 C with continuous agitation

Question 28

how is single donor plasma stored?

Answer 28

frozen within 8 hours of collection if CPD anti coagulation is used frozen within 6 hours if ACD is used PF24 stored at -18 C for 1 year

Question 29

how is cryoprecipitate stored?

Answer 29

removed from plasma and stored at -18 C or colder. expires 1 year from collection

Question 30

how is RH Immune Globulin stored?

Answer 30

stored at 1-6 C with expiration date based on manufacturers label.

Question 31

what are the approved doses for RH immune globulin?

Answer 31

for IV preparations, 120ug or 300ug For IM preparations, 300 ug

Question 32

how are red blood cells frozen?

Answer 32

frozen with glycerol. they can be stored for up to 10 years. they are frozen

Question 33

what are the 2 methods used to freeze rbcs

Answer 33

high glycerol method. low glycerol method.

Question 34

what does the high glycerol method include?

Answer 34

frozen at -80 C most widely used procedure frozen within 6 days when using CPD or 42 days when preserved using AS 1,3, or 5

Question 35

what temp are rbcs frozen at using the low glycerol method?

Answer 35

-120 C

Question 36

what is used to rejuvenate rbcs

Answer 36

rejuvesol

Question 37

what is the shipping procedure for non frozen blood?

Answer 37

packed up to 30 liquid rbc units in a reusable cardboard and styrofoam standard liquid shipping container. covered with 14 pounds of CUBED WET ice.

Question 38

the blood bank is divided into distinct areas, what are the functions?

Answer 38

Component preparation and storage donor processing product labeling main laboratory reference laboratory area

Question 39

what is intraoperative collection?

Answer 39

it involves collecting blood from the surgical site using a draining tube. the blood lost from patient is reinfused into the patient.

Question 40

what is apheresis?

Question 41

what are some of the problems with apheresis?

Answer 41

citrate toxicity vasovagal reactions hypovolemia