DOENÇAS INFLAMTORIAS Flashcards

1
Q

DESMOGLEINA

A

PARTE DO QUERATINOCITO QUE ANCORA ENTRE AS CELULAS EPIDERMICAS(TEM DESMOGLEINA 1 E 3)

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2
Q

QUAL A DOENÇA BOLHOSA MAIS COMUM ENTRE CRIANÇAS?

A

PENFIGO FOLIACEO

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3
Q

ANTICORPO NO PENFIGO FOLIACEO

A

IGG ONTRA DESMOGLEINA 1

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4
Q

QUADRO CLINICO DO PENFIO FOLIACEO

A

DESCAMAÇAO,EROSOES E CROSTAS
EM AREAS FOTOEXPOSTAS
SINAL DE NIKOLSKY=ACANTOLISE

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5
Q

DX DO PENFIGO FOLIACEO

A

AP:BOLHA SUBCORNEA
IFD:IGG INERCELULAR ALTO
IFI:AC CIRCULANTES= ATIVIDADE

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6
Q

TTT DO PENFIGO FOLIACEO

A

CASOS LEVES:CE TOPICO
PREDNISONA 0.5-1 MG/KG
AZATIOPRINA E MICOFENOLATO
CASOS GRAVES:PLASMAFERES E IMUNOGLOBULINA

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7
Q

QUAL A DIFERENÇA ENTRE PEFIGO FOLIACEO E PENFIGO VULGAR

A

O PENFIGO VULGAR ACOMETE DESMOGELINA 1 E 3.A DES MOGELINA 3 ESTA NAS MUCOSAS LOGO NO PENFIGO VULGAR HA ACOMETIMENTO DE PELE E MUCOSAS

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8
Q

FAIXA ETARIA DO PENFIGO VULGAR

A

ACOMETE MAIS IDOSOS

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9
Q

ETIOLOGIA DO PENFIGO VULGAR

A

AUTO IMUNE OU MEDICAMENTOS(CAPTOPRIL,PENICILAMINA E RIFAMPICINA

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10
Q

QUADRO CLINICO DO PENFIGO VULGAR

A

BOLHAS,EROSSOES
QUEDA DO ESTADO GERAL
SINAL DE NIKOLSKY E SINAL DE ASBOE HANSEN

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11
Q

SINAL DE ASBOE HANSEN

A

APERTA A BOLHA E ELA EXPANDE PARA O LADO

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12
Q

DX DO PENFIGO VULGAR

A

AP:BOLHA SUPRA BASAL
IFD:IGG INTERCELULAR
IFI:AC CIRCULANTES= ATIVIDADE

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13
Q

TTT DO PENFIIGO VULGAR

A

PREDNISONA
AZATIOPRINA
MICOFENOLATO
RESGATE:IMUNOGLOBULINA
RITUXIMABE

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14
Q

DERMATITE HERPETIFORME GENEREALIDADES

A

DOENÇA DE DUHRING
ENTEROPATIA SENSIVEL AO GLUTEN(MANIFESTAÇAO CUTANEA DA DOENÇA CELIACA)

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15
Q

ANTICORPO NA DERMATITE HERPETIFORME

A

IGA DEPOSITADA NAS PAPILAS DERMICAS

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16
Q

QUADRO CLINICO DA DERAMTITE HERPETIFORME

A

VESICULAS AGRUPADAS/ESCORIAÇOES
10%-SINTOMAS TGI
ASSOCIAÇAO:MIASTENIA GRAVE,TIREOIDITE E ANEMIA PERNICIOSA

17
Q

DX DA DERMATITE HERPETIFORME

A

AP:BOLHAS SUBERPIDERMICAS + MICROABSCESSOS DE PAPILA
IFD:DEPOSITO GRANULAS DE IGA

18
Q

ANTICORPOS DA DERAMTITE HERPETIFORME

A

ANTITRANSGLUTAMINASE
ANTIGLIADINA
ANTIENDOMISIO

19
Q

TTT DA DERMATITE HERPETIFORME

A

DAPSONA:ANEMIA HEMOLITICA E HEPATIE
DIETA LIVRE DE GLUTEN

20
Q

PENFIGOIDE BOLHOSO

A

CLIVAGEM SUBEPIDERMICA

21
Q

QUADRO CLINICO DO PENFIGOIDE BOLHOSO

A

AGUDO/SUBAGUDO
BOLHAS TENSAS
PRURIDO
NIKOLSKY NEGATIVO

22
Q

DX

A

AP:BOLHA SUBEPIDERMICA + EOSINOFILOS
IFD:DEPOSITO DE C3 EM ZMB

23
Q

TTT

A

TETRACICLINA + PREDNISONA