DNA-RNA-PROTIEN Flashcards
steps in DNA replication
complimentary base pairing produces semiconservative replication
1. helicases unwind the parental double helix
2. single stranded binding proteins stabilize the unwound parental DNA
3. the leading strand is synthesized continually in the 5’-3’ direction by DNA polymerase
4. promise synthesizes a short RNA primer, which is extended by a DNA polymerase to form an Okazaki fragment
5. after RNA. polymerase os replaced by DNA, DNA ligase joins the Okazaki fragment to the growing strand
pol 3
produces new strands of complimentary DNA
pol 1
fills in the gaps between newly synthesized Okazaki fragments
DNA helicase
unwinds double helicase
single stranded bonded protiens
keeps helix open
primase
creates RNA primers to initiate synthesis
ligase
welds together Okazaki fragments
topoisomerase
enzyme that relaxes super coils by nicking strands
replication is ….
bidirectional
replication forks move
in opposite directions form 5’ –> 3’ or 3’ –> 5’
redundancy
basis for repair of errors that occur during replication or storage
meiotic recombination process
- homologs physically break, exchange parts and rejoin
- recombination can occur anywhere along the DNA molecule
- precision in the exchange can give rise to unequal yield of 2 different alleles, 50% of alleles are associated w/ crossing over and 50% aren’t
difference in DNA and RNA
each nucleotide contains ribose instead of deoxyribose
single stranded and less stable than DNA
bases of RNA
U, A, G, C
central dogma of DNA
DNA –> (transcription) RNA –> (translation) Protiens