DNA replication eukaryotes review Flashcards

1
Q

ORC and CDT1

A

bind origin

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2
Q

RPA

A

binds ssDNA to stabilize

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3
Q

when will the cell enter S phase?

A

after sufficient accumulation of cyclin A-CDK2

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4
Q

components of eukaryotic helicase

A

MCM2-3, (CDC45 + GINs = CMG)

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5
Q

primase in eukaryotes

A

polymerase alpha primase

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6
Q

RFC

A

clamp loader

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7
Q

PCNA

A

sliding clamp

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8
Q

pol for leading strand

A

DNA pol episilon

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9
Q

pol for lagging strand

A

DNA pol delta

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10
Q

RNA primer replacement

A

RNase H1 + FEN1 + DNA pol delta

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11
Q

termination

A

telomerase

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12
Q

what links the helices and polymerase?

A

fork protection complex

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