DNA replication eukaryotes review Flashcards
1
Q
ORC and CDT1
A
bind origin
2
Q
RPA
A
binds ssDNA to stabilize
3
Q
when will the cell enter S phase?
A
after sufficient accumulation of cyclin A-CDK2
4
Q
components of eukaryotic helicase
A
MCM2-3, (CDC45 + GINs = CMG)
5
Q
primase in eukaryotes
A
polymerase alpha primase
6
Q
RFC
A
clamp loader
7
Q
PCNA
A
sliding clamp
8
Q
pol for leading strand
A
DNA pol episilon
9
Q
pol for lagging strand
A
DNA pol delta
10
Q
RNA primer replacement
A
RNase H1 + FEN1 + DNA pol delta
11
Q
termination
A
telomerase
12
Q
what links the helices and polymerase?
A
fork protection complex