Dna Replication Flashcards
Main ezymes involved in dna replication
Helicase Single strand binding proteins Primase Dna polymerase Exonuclease Dna ligase
Helicase
Unwinds dna helix
Single strand binding proteins
Stabilise seperate strands
Primase
Adds a short Rna primer to Dna strand
Dna polymerase
Binds nucleotides to form new strands
Exonuclease
Removes Rna primer and inserts correct base
Dna ligase
Joins okazaki fragments and seals other nicks in sugar-phosphate backbone
Types of mutations
Point mutation Deletion mutation Insertion mutation Frameshift mutation Inversion mutation
Point mutation
Change of base pair
Deletion mutation
Removal of one or more bases
Insertion mutation
Insertion of one or more bases (portion of dna sequence reversed)
Frameshift mutation
Deletion or insertion of a number of bases that cannot be dovided by 3
Inversion mutation
Inversion of a sequence of bases (may cause frameshift)
Point mutation, silent mutation
Codes for the same animo acid
Point mutation, missence mutation
Codes for a different amino acid