Dna Replication Flashcards

1
Q

Main ezymes involved in dna replication

A
Helicase
Single strand binding proteins
Primase
Dna polymerase
Exonuclease
Dna ligase
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2
Q

Helicase

A

Unwinds dna helix

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3
Q

Single strand binding proteins

A

Stabilise seperate strands

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4
Q

Primase

A

Adds a short Rna primer to Dna strand

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5
Q

Dna polymerase

A

Binds nucleotides to form new strands

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6
Q

Exonuclease

A

Removes Rna primer and inserts correct base

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7
Q

Dna ligase

A

Joins okazaki fragments and seals other nicks in sugar-phosphate backbone

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8
Q

Types of mutations

A
Point mutation
Deletion mutation
Insertion mutation
Frameshift mutation
Inversion mutation
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9
Q

Point mutation

A

Change of base pair

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10
Q

Deletion mutation

A

Removal of one or more bases

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11
Q

Insertion mutation

A

Insertion of one or more bases (portion of dna sequence reversed)

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12
Q

Frameshift mutation

A

Deletion or insertion of a number of bases that cannot be dovided by 3

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13
Q

Inversion mutation

A

Inversion of a sequence of bases (may cause frameshift)

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14
Q

Point mutation, silent mutation

A

Codes for the same animo acid

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15
Q

Point mutation, missence mutation

A

Codes for a different amino acid

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16
Q

Point mutation, nonsense mutation

A

Codes for a stop, which can trunate the protein

17
Q

Translocation

A

A piece of chromosome attaches to another chromosome

18
Q

Point mutation, transition

A

Exchanges a purine for a purine

19
Q

Point mutation, transversion

A

Exchanges a purine for a pyrimidine or pyrimidine for a purine