DNA Replication Flashcards
It is an enzyme that unzips the DNA strands by breaking the hydrogen bonds between the complementary bases
It helps create a REPLICATION FORK
Helicase
It is an enzyme that breaks, swivels and rejoins the DNA ahead of the replication fork, relieving the strain caused by unwinding
Topoisomerase
It is an enzyme that synthesizes RNA primers, using the parental DNA as a template
It is about 5-10 nucleotides longs
Primase
It is the main enzyme in the DNA Replication process
It synthesizes new necleotides that are complementary to the strands
DNA Polymerase III
It is an enzyme that removes primer from the lagging strand and also fills the gap
DNA Polymerase I
It is an enzyme that catalyzes the formation of a phosphodiester bond between nucleotides on one strand of a double-stranded DNA molecule
Ligase
Steps of DNA replication
- Separation - Helicase
- Binding - Primase
- Complementation - Polymerase III
- Formation - Polymerase I
- Closing - Ligase
