DNA Replication Flashcards
Separates DNA strands into 2 templates
Helicase
Creates RNA primers required to start replication
Primase
It binds with primer , builds new strand, replicative enzyme
DNA polymerase I and II
Removes primer in lagging strand
DNA polymerase 1
What does 3’ to 5’ exonuclease activity do?
Proofread
What does 5’to 3’ exonuclease activity do?
Remove primers
Only synthesizes short sequence of new DNA
DNA polymerase 1
Synthesizes long sequence of new DNA
DNA polymerase 3
Process during which a double stranded DNA molecule is copied to produce two identical DNA molecules
DNA replication
Principle in which nitrogenous bases of the DNA molecules bond with one another
Base pairing
Building block of nucleic acids
Nucleotides
Structure of two strands, intertwining around an axis like a twisted ladder
Double helix
This enzymes replicates DNA molecules to actually build new strand of DNA
Dna polymerase
This makes the primer so that DNA polymerase ca figure out where to go to start to work
Primase
It helps glue DNA fragments
Ligase
It keeps the dna from supercoiling
Topoisomerase
The enzyme required for dna
Dna polymerase 3
Enzyme required for repair
Dna polymerase 1 and 2
The area where dna replication takes place
Replication fork
The short lengths of DNA that are produced by the discontinuous replication of the lagging strand
Okazaki fragments
A circumstances where the expression of one gene is modified by the expression of one or more other genes
Epistasis
Prevents over winding of the DNA double helix ahead of the replication fork
Topoisomerase
A post-transcriptional modification in which a single gene can code for multiple proteins
Gene splicing
Involves using enzymes and various laboratory techniques to manipulate and isolate DNA segemnt
RRecombinant DNA
