DNA - Overall Study Flashcards

1
Q

What is the name of the molecule of genetic code that leaves the nucleus of the cell during translation?

A

mRNA

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2
Q

Who made the Watson-Crick model?

A

James Watson and Francis Crick

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3
Q

Define genetics

A

The study of inherited traits

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4
Q

What three parts make up nucleotides?

A

Phosphate group, deoxyribose sugar (pentose sugar)`, nitrogen-rich bases

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5
Q

What was the first successful DNA model?

A

The Watson-Crick model?

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6
Q

TRUE or FALSE

The genes that code for a particular characteristic are located on different parts of the paired autosomes.

A

False - They are located at the same parts of paired autosomes.

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7
Q

What are the three characteristics of homologous chromosomes?

A
  1. Same length
  2. Have a structure called the centromere
  3. Have genes for particular characteristics at the same location along their length.
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8
Q

What does asexual reproduction rely on?

A

Mitosis

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9
Q

What are the three steps of DNA replication?

A
  1. The strands of DNA separate from each other (unzip)
  2. Nucleotides that are not yet part of a DNA chain pair up with the exposed nucleotides.
  3. Zips back up
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10
Q

Define meiosis

A

The process of cell division that produces gametes - sperm and egg cells

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11
Q

What is a chromosome?

A

A long, thin, thread-like structure found in the nuclei of all cells that contain a nucleus.

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12
Q

What causes mutations?

A

Either spontaneously (due to a fail in replication) or damage to a strand of DNA.

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13
Q

What are the smaller molecules that make up the structure of DNA called?

A

Nucleotides

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14
Q

Give an example of a mutagen caused by radiation

A

X-rays, radioisotopes, UV light

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15
Q

Give an example of a mutagen caused by something biological

A

Hepatitis B, cervical cancer

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16
Q

Give an example of a mutagen caused by something chemical

A

Cigarette smoke, asbestos, mustard gas

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17
Q

What are the different types of mutations?

A

Silence mutation. Missense. Nonsense. Frameshift

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18
Q

What does a silence mutation do?

A

Nothing, it does not affect the individual

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19
Q

What does a missense mutation do?

A

Causes the wrong protein to be produced

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20
Q

What does a nonsense mutation do?

A

The code abruptly ends, stopping the production of proteins

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21
Q

What does a frameshift mutation do?

A

Insertion or deletion of bases. The information becomes jumbled and impossible to read.

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22
Q

What are the groups of proteins?

A

Structural. Enzymes. Regulatory

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23
Q

Define genes

A

Genes are sections of DNA arranged along the chromosomes

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24
Q

Define ribosomes

A

A molecular machine that builds proteins from amino acids

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25
What forms the backbone of the DNA molecule?
Phosphate group and the deoxyribose sugar.
26
What does a gene code for?
A specific protein
27
What are homologous chromosomes?
A pair of autosomes
28
How many chromosomes are in the human body?
46 (23 pairs)
29
What are gametes?
Sperm and egg cells
30
What are the stages of meiosis
Prophase, crossover, metaphase1, anaphase1, telophase1, metaphase2, anaphase2, telophase2
31
What case-letter is the dominant trait represented with?
uppercase
32
What case-letter is the recessive trait represented with?
lowercase
33
Define codon
Bases arranged in triplets; a series of bases
34
Define translation
When RNA is read by the ribosomes
35
Give an example of an organism that reproduces asexually.
Hydra, yeasts, grasses
36
What happens within metaphase?
Chromosomes meet in the middle and become attached by spindle fibers.
37
Define replication
The process of copying DNA
38
What happens within interphase?
The genetic material doubles and prepares to divide
39
Define phenotype
The observable characteristic of the individual
40
What are the complementary base pairings?
Adenine thymine | Guanine cytosine
41
What is cytokinesis?
The final stage of mitosis; when the cell divides
42
What sex chromosome pair determines the female sex?
XX
43
What sex chromosome pair determines the male sex?
XY
44
What does DNA stand for?
Deoxyribonucleic acid
45
What are the non-sex chromosomes called?
autosomes
46
What are the stages of mitosis?
Interphase, prophase, metaphase, anaphase, telophase, cytokinesis
47
What is the advantage of sexual reproduction in comparison to asexual reproduction?
There is greater variation within offspring
48
Define mutagen
Agents that cause mutations
49
What is a sex-linked gene?
A gene found on one of the chromosomes that determine the sex of offspring
50
Which backbone of the DNA molecule do the nitrogen-rich bases join to?
Phosphate group
51
What reads codons?
Ribosomes
52
Define transcription
The process of DNA being copied to RNA
53
What are the four nitrogen-rich bases?
Adenine (A), thymine (T), guanine (G), cytosine (C)
54
What happens within anaphase?
Chromosomes get pulled apart by the spindle fibers. There is now one chromatin on each side
55
What is a centromere?
The point on a chromosomes where the two chromatids are joined together.
56
TRUE or FALSE | Daughter cells are not genetically identical to the parent cell.
FALSE
57
Where are chromosomes located?
In the nucleus of a cell. DNA can be found in the mitochondria or chloroplasts
58
What happens within telophase?
Chromosomes uncoil in chromatids. Spindle fibers disintegrate. Centrioles replicate. Membrane is formed.
59
What is asexual reproduction?
Offspring that isn't produced by the union of gametes and is instead produced through mitosis.
60
What is Chargaff's rule?
There is a similar amount of adenine and thymine as there is to guanine and cytosine.
61
Define DNA
The molecule that determines the specific characteristics of an individual
62
Explain why gametes have to have half the diploid number of chromosomes (2n).
If each parent passed on a complete set of genetic information, the offspring would 4n chromosomes. Then their offspring would have 8n and so on.
63
What is a mutation?
A mutation is when a mistake occurs in the copying of DNA
64
Are mutations always dangerous? Why?
No. They can create different or even beneficial versions of a protein. Mutations can add to the diversity of organisms
65
Define carcinogen
A mutation that causes cancer
66
TRUE or FALSE | Any pair of alleles that has a dominant trait present will produce that dominant trait.
True
67
Explain Punnett squares
Punnett squares are a visual way of showing all the possible types of offspring that results from a cross.
68
Define genotypes
The actual genetic information carried by an individual
69
What happens within prophase?
Chromatids join by the centromere. Centrioles move to opposite sides of the nucleus. Nucleolus disappears. Nuclear membrane disintegrates.