DNA Inhibitors - Fluoroquinolones and Metronidazole Flashcards

1
Q

Quinolone:

Nalidixic acid (NegGram)

A

Effective against enteric Gram - bacteria. NOT Pseudomonas

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2
Q

Norfloxacin (Noroxin)

A

Excellent Gram + coverage

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3
Q

Lomefloxacin (Maxaquin)

Ofloxacin (Floxin)

Ciprofloxacin (Cipro)

A

Excellent Gram - and some Gram +

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4
Q

Moxifloxacin (Avelox)

A

Does not cover pseudomonas aeruginosa

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5
Q

Gemifloxacin (factive)

A

Acute bacterial exacerbation of chronic bronchitis and mild-moderate pneumonia

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6
Q

Levofloxacin (Levaquin)

A

Excellent Gram - coverage and improved Staph coverage. Treats Legionella and Chlamydia atypical pneumonia

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7
Q

Metronidazole (Flagyl)

A

Kills obligate anaerobes and Protozoans

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8
Q

Nitrofurantoin (Macrodantin)

A

Kills many urinary pathogens, but NOT Pseudomonas, Klebsiella, Proteus, Serratia, Acinetobacter

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