Cephalosporins

Question 1

1st
Oral:

Cephalexin (Keflex)

Cefadroxil

Answer 1

Gram + cocci except enterococci and MRSA

Some Gram - enterics. Not effective against anaerobes

Question 2

2nd
Oral:

Cefaclor (Ceclor)

Cefprozil

Answer 2

Gram + cocci. Extended Gram - activity. NOT effective against Pseudomonas. Used for otitis media, pharyngitis, and sinus, skin, and respiratory infxns.

Question 3

1st
Parenteral:

Cefazolin (Kefzol)

Answer 3

Surgical prophylaxis and for tx of skin/soft tissue infxns caused by Staph or Strep.

Question 4

2nd
Oral or Parenteral:

Cefuroxime

Answer 4

Gram + cocci. Extended Gram - activity. NOT effective against Pseudomonas. Used for otitis media, pharyngitis, and sinus, skin, and respiratory infxns.
Single dose for N. gonorrhoeae.

Question 5

2nd
Parenteral:

Cefoxitin
Cefotetan

Answer 5

Gram + cocci. Extended Gram - activity. NOT effective against Pseudomonas. Used for otitis media, pharyngitis, and sinus, skin, and respiratory infxns.

Question 6

3rd
Parenteral:

Ceftriaxone (Rocephin)
Cefotaxime
Ceftazidime (Fortaz)
Ceftizoxime
Cefepime

Answer 6

Gram - bacilli (resistant to other cephalosporins, penicillins, aminoglycosides). Variable efficacy against Pseudomonads. Gram + cocci (incl. Staph and nonenteric Strep)

Question 7

3rd
Oral:

Ceftibuten
Cefpodoxime
Cefdinir
Cefditorin

Answer 7

Gram - bacilli (resistant to other cephalosporins, penicillins, aminoglycosides). Variable efficacy against Pseudomonads. Gram + cocci (incl. Staph and nonenteric Strep)