DNA, genes and chromosomes Flashcards
what does prokaryote mean
before the nucleus
prokaryotic DNA circular or linear
circular
what DNA do prokaryotes contain
a single, circular chromosomal DNA molecules
what is the single, circular chromosomal DNA in prokaryotes sometimes reffered to as
nucleoid
what are plasmids
very small circular DNA molecules
how many genes do plasmids contains
a few
why are plasmids used
more accessible for proteins requires for a gene expression and therefore contain genes that are requires often, quickly and in emergencies
where are genes for antibiotic resistance found
plasmids
prokaryotic DNA protein association
not associated with any proteins
eukaryotic DNA protein association
histone proteins
what are chromosomes (eukaryotic) made of
one long, condensed DNA molecules associated with histone proteins
role of histone proteins
organise and condense the DNA tightly to fit into the nucleus
what are the other proteins (not histone) used for in eukaryotic chromosomes
enzymes used in copying and repairing DNA
what is chromatin
tightly coiled combination of DNA and proteins
what are chromatids and chromosomes made of
chromatin
what happens during s phase of interphase
the DNA replicates to create two identical strands of DNA called chromatids joined together by a narrow region called the centromere
what are sister chromatids
two chromatids that make up the double structure of a chromosome
why is important sister chromatids are identical
key to cell division as one chromatid goes into one daughter cell and one to the other during mitosis ensuring daughter cells are genitally identical
what is a chromatid made of
a very long, condensed DNA molecules, which is made up of a series of genes
how are ends of the chromatids in the chromosome
sealed with protective structures called telomeres
what DNA is mitochondrial and chloroplast DNA most similar to
prokaryotic
what is mitochondria and chloroplast DNA like
short, circular and not associated with proteins
Mitochondria + chloroplast DNA
small circular pieces of DNA
what organelles contains their own DNA
mitochondria and chloroplast
what is a gene
base sequence of DNA that codes for the amino acids sequence of a polypeptide or functional RNA molecule
how is mRNA used
base sequences on mRNA molecules are used by ribosomes to form polypeptide chains
how is tRNA used
amino acids are carried to the ribosome by tRNA molecules
how is rRNA used
rRNA molecules form part of the structure of ribososmes
what does shape and behavior of a proteins molecule depend on
the exact sequence of amino acids (primary structure of the protein)
what do genes in DNA molecules control
protein structure as they determine they exact sequence of amino acids joined together when proteins are synthesied in the cell
what is DNA essential for
cell survival
what does every chromosome consist of
a long DNA molecules and its associated protein
what does every chromosome consist of
a long DNA molecule that codes for several different proteins
what is a locus
position of a gene on a chromosome
what can different alleles of a gene have
slightly different nucleotide sequence but still occupy the same locus on the chromosome
gene
base sequence of DNA that codes for the amino acid sequence of polypeptide or functioning DNA
3 features of prokaryotic DNA
short, circular and not associated with proteins
3 features of eukaryotic DNA
very long, linear and associated with histone proteins
what is the DNA nucleotide base code found within the gene
a triplet code
how many bases code for 1 amino acid
3
triplets of bases known as
codons
how many amino acids are there
20
what are start and stop signals
triplets of bases which tell the cell where the individual genes starts and stop
what do start and stop signals ensure
the cell reads the DNA correctly and can produce the correct sequences of amino acids that require it to function properly
how many triplets are possible
64
what is degenerate genetic code
multiple codons code for the same amino acid
what can degenerate code limit
effect of mutations
what is universal genetic code
all organisms use the same code (few exceptions)
what does universal code mean
same codons code for same amino acids in all living things so genetic information is transferable between species)
3 features of genetic code
non-overlapping, degenerate and universal
what does genetic code being non-overlapping mean
each base triplet is read in sequence, separate from specific amino acid before and after it. base triplets don’t share their bases
which type of cell is non-coding DNA found in
eukaryotic
what is non-coding DNA
does not code for any amino acids
where can non-coding DNA be found
between genes and within genes
how is non-coding DNA found between genes
as non-coding multiple repeats which means they contain the same base sequences repeated multiple times
what is the non-coding DNA within genes called
introns
how are exons separated
one or more introns
what are coding sections of DNA called
exons
what is transcribed in transcription
they whole gene (introns and exons) to produce pre-mRNA molecules
what is produced in transcription
pre-mRNA molecules
what happens before pre-mRNA leaves the nucleus
splicing
what is splicing
removing the introns (non-coding sections) and joining together the exons (coding sections)