DNA, genes and chromosomes Flashcards

1
Q

in prokaryotic cells

A

DNA molecules are short, circular and not associated with proteins

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2
Q

in the nucleus of eukaryotic cells

A

DNA molecules are very long, linear and associated with proteins called histones

together a DNA molecule and its associated proteins form a chromosome

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3
Q

mitochondria and chloroplasts of eukaryotic cells

A

contain DNA, like the DNA of prokaryotes - short, circular and not associated with proteins

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4
Q

a gene

A

a gene is a base sequence of DNA that codes for:

the amino acid sequence of a polypeptide

a functional RNA - rRNA and tRNA

it occupies a fixed position called a locus on a particular DNA molecule

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5
Q

a triplet

A

a sequence of 3 DNA bases - codes for a specific amino acid

the genetic code is universal, non-overlapping and degenerate

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6
Q

nuclear DNA coding in eukaryotes

A

much of the nuclear DNA does not code for polypeptides

for example - non-coding multiple repeats of base sequences between genes

even within a gene - only some sequences called exons code for amino acid sequences

within the gene, these exons are separated by one or more non-coding sequences called introns

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7
Q

gene

A

a sequence of DNA bases at a specific locus which codes for a specific polypeptide or a functional RNA

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8
Q

locus

A

location / position on the chromosomes

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9
Q

allele

A

an alternative form of a gene

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10
Q

promoter

A

promoter sequence to indicate start of the gene

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11
Q

introns

A

are base sequences within the gene that do not code for amino acids

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12
Q

exons

A

are base sequences that code for amino acids

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13
Q

what are the three components of nucleotides

A

a pentose sugar

a phosphate group

an organic base

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14
Q

describe the structure of DNA

A

made up of a deoxyribose sugar, a phosphate group and one of the four organic bases A C G T

it is double stranded

hydrogen bonds between bases form a helix shape

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15
Q

describe the role of DNA

A

carries genetic information, determines our inherited characteristics

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16
Q

describe the structure of RNA

A

made up of ribose sugar, a phosphate group and one of four organic bases A C G U

it is single stranded

17
Q

describe role of RNA

A

transfers genetic information from DNA to ribosomes for protein synthesis

18
Q

which bases are purine and which are pyrimidine

A

purine (double ring) - adenine, guanine

pyrimidine (single ring) - cytosine, thymine, uracil

19
Q

how is DNA in eukaryotic cells different from in prokaryotic cells

A

eukaryotic cells = found in nucleus, long and linear, associated with proteins called histones to form chromosomes, mitochondria and chloroplasts contain prokaryotic like DNA

prokaryotic cells = short and circular, not associated with proteins

20
Q

what is genetic code

A

the order of bases on DNA

consists of codons (triplets of bases that code for a particular amino acid)

21
Q

identify features of the genetic code

A

non-overlapping = each triplet is only read once

degenerate = more than one triplet codes for the same amino acid (64 possible triplets for 20 aa)

universal = same bases and sequences used by all species

22
Q

what is a gene

A

a sequence of bases on a DNA molecule that codes for a specific sequence of amino acids to make a polypeptide

can also code for functional RNA

23
Q

what is a locus

A

the fixed position on a DNA molecule occupied by a gene

24
Q

what is an allele

A

different versions of the same gene, found at the same locus on a chromosome

25
Q

what are exons and introns

A

exons = regions of DNA that code for amino acid sequences - separated by one or more introns

introns = regions of DNA that do not code for anything

26
Q

where are introns found

A

between exons within genes