Dna And Protein Synthesis Flashcards

1
Q

genes

A

sequence of DNA nucleotides coding for protein

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2
Q

structure of DNA

A

double helix joined by phosodiseter bonds
due to condensation reaction
A, T , C, G nitrogenous bases between h bonds
polymer
dexribose sugar

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3
Q

helix

A

compact shape
protection

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4
Q

double strand

A

acts as template
prtection
stability

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5
Q

DNA replication are semi consertative

A

dna helixase breaks the hydrogen bonds seperate the starns to each acts as template
dna nucleotides exposed joined by by specific complematry baes A and T , C and G
DNA polymerase joines the 2 strands by phosphodieter bonds

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6
Q

structure of mRNA and functions

A

synthesis of protein
linear
condon

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7
Q

structure and functions of tRNA

A

clover shape
anticodon
binding site for the specific amino acids

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8
Q

RNA structure

A

pentrose sugar
U and A , C and G
single strands

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9
Q

dna in prokaryotes

A

shorter
not associates with protein
circular

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10
Q

alleles

A

different version of the same genes

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11
Q

homologous pair

A

2 chroomsomes one from paternal and another from maternal
joined by centrmer
determining the same charactersitc or genes but could be different alleles

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12
Q

genetic codes features

A

non- overlappig
universal
degenerate

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13
Q

introns

A

non coding bases

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14
Q

multiplies repeats

A

same bases sequence ocuuring again and again in DNA that are sometime non-coding

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15
Q

genome

A

complete set of genes

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16
Q

protenome

A

full range of protein

17
Q

transcription steps

A

nucleus
unwinds of strands acts as template
rna nucleoides along dna nucleotides bases U with A , C and G
using RNA polymerase
spilicing occurs removed intons andf only exons left

18
Q

translation

A

mRNA binds to ribosomes
tRNA with complemantary anticodon binds to codon on mRNA
ribosomes has 2 binding sites 2 tRNA and mRNA codon can binds together
-2 amino acids from 1st and 2nd tRNA joins by peptide bond via condensation
- tRNA moves away from ribosome leaving amino acid collecting another amino acid from pool
- ribosomes moves along mRNA until reaches stop codon

19
Q

genetic codes for dna and trna

A

are the same execpt thymin replces uracil

20
Q

substition

A

non-functional protein/functional
replacement of single base

21
Q

deletion

A

frame shirt
non-functional protein

22
Q

addidition

A

frame shirt
non-functional protein

23
Q

inversion

A

sequence are reversed

24
Q

translocation

A

sequence bases is moved from 1 location to another part of geonome

25
Q

how effects of mutation ?

A

hydrogen and ionic bonds , disulfied bond alteration
alteration in active site
tertiary structure alteration

26
Q

proto-oncogenes

A

stimulates cell division
mutated oncogene stimualted todovoode too quickly

27
Q

tumour suppressor genes

A

slow cel divsion
- mutated causes to divide too quicly

28
Q

transcription factor

A

protein
binds to promoter region within DNA stimulates / inibiting transcription

29
Q

regulation of transcription by oestrogen

A

lipid and steriod
bind to receptor to TF
enter nucleus
binding oestrogen change shape of TF to become specifically to promoter sequence
RNA polymerase attath +catalyse
increase the expession

30
Q

regulation of translation

A
  • double strands RNA broken down by enzyme into siRNA
  • each strands with enzyme binds
  • siRNA strands pairs with complemantary base on mRNA
  • enzyme cuts the mRNA in to smaller seaction