DNA Flashcards
relationship between chromosomes, DNA, genes
chromosomes is condensed DNA, genes are short sections of DNA
why does DNA need to replicate
- to produce new cells, pass genetic information to ‘daughter’ cells
- for growth + general replacement when other cells die
- to heal injuries
shape of DNA
made up of two strands, twisted into a double helix
four types of nitrogenous bases
- adenine
- guanine
- thymine
- cytosine
function of helicase in DNA replication
to unzip the DNA; creating a replication fork of DNA stands after they are separated
function of primase in DNA replication
creates an RNA primer, which takes bases and matches their corresponding DNA bits
function of polymerase III in DNA replication
creates new DNA/adds DNA bases from 5 to 3 end
difference between leading strand and lagging strand
leading strand: DNA made continuously after primer; goes from 5 to 3
lagging strand: goes from 3 to 5; DNA must be made in Okazaki fragments
Okazaki fragment
a small section of DNA, created on the lagging strand before two primers
function of polymerase 1in DNA replication
uses exonuclease activity to remove primers and fill gaps with DNA bases
function of ligase in DNA replication
seals up DNA strands and makes it one continuous strand of DNA
nitrogenous bases
ACTG, is the ‘information’
sugar phosphate backbone
two of them, creates the ‘rails’ of the DNA
base pairings
C + G, A + T
DNA groups
deoxyribose sugar, phosphate, nitrogenous bases