DMD

Question 1

Def

Answer 1

X linked recessive
Dystrophin
Start 3-5 y.o
1st affected muscles (pelvis,thighs and shoulders)

Question 2

CP:

Answer 2

Toddlers: pseudohypertrophy
Preschoolers: trouble getting up from the floor or climbing
Schoolers: waddling gate
Wheel chair at 7-12 y.o

Question 3

Complications

Answer 3

Cardiomyopathy and respiratory muscles affection (serious)

Dilated cardiomyopathy: common cause of death

Question 4

Dx

Answer 4

Enzyme tests
Genetic test
EMG
Muscle biopsy

Question 5

Tx

Answer 5

Glucocorticoids (prednisone and deflazacort).

Assistive devices: For stretching exercises and mobility aids (wheelchair).