DM2 Pt1-3 Cat Flu (FCV & FHV) Flashcards

1
Q

What is the general term used for upper respiratory tract infections in cats?

A

Cat flu is the general term used for upper respiratory tract infections in cats.

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2
Q

What are the two main viral causes of cat flu?

A

Feline Calicivirus (FCV) and Feline Herpesvirus (FHV).

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3
Q

What other pathogens can cause flu-like symptoms in cats besides FCV and FHV?

A

Bordetella bronchiseptica and Chlamydophila felis.

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4
Q

How is FCV mainly transmitted?

A

FCV is shed predominantly in oral and nasal secretions during acute disease.

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5
Q

What proportion of cats continue shedding FCV after recovery?

A

Up to 40% of cats continue shedding FCV after recovery, with a few shedding for several years.

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6
Q

How does FCV evolve quickly, making vaccination challenging?

A

FCV has a small, single-stranded RNA genome that evolves quickly, constantly changing.

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7
Q

What is acute oral and upper respiratory tract disease associated with FCV?

A

It mainly affects kittens and causes oral ulceration, sneezing, and serous nasal discharge.

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8
Q

What are the possible complications of FCV in young or sick cats?

A

Complications include pneumonia, secondary bacterial infections, and death.

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9
Q

What is chronic stomatitis in cats, and how is it related to FCV?

A

Chronic stomatitis is a proliferative/ulcerative faucitis, possibly an immune reaction to FCV.

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10
Q

What is limping syndrome in relation to FCV?

A

Limping syndrome is an acute, transient lameness with fever that can follow FCV infection or vaccination.

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11
Q

What characterizes virulent systemic FCV disease?

A

It is characterized by systemic inflammatory response syndrome, disseminated intravascular coagulation, multiorgan failure, and death.

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12
Q

What is the mortality rate of virulent systemic FCV disease?

A

Mortality rates can reach up to 67%.

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13
Q

Why is strict hygiene important in practices dealing with FCV outbreaks?

A

It helps prevent outbreaks of virulent systemic FCV disease.

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14
Q

How can FCV be diagnosed?

A

FCV can be diagnosed by virus isolation or PCR, using conjunctival, oral, blood, or tissue samples.

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15
Q

What should be considered when interpreting positive PCR results for FCV?

A

Positive PCR results may reflect low-level shedding by carriers, so they don’t confirm FCV as the cause of disease.

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16
Q

How is virulent systemic FCV disease diagnosed?

A

It is diagnosed based on clinical signs and isolation of the same strain from the blood of several diseased cats.

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17
Q

How do maternally derived antibodies affect vaccination in kittens?

A

Maternally derived antibodies protect kittens in early weeks but may interfere with vaccination, and they persist longer than FHV antibodies.

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18
Q

When do virus-neutralizing antibodies typically appear after FCV infection?

A

They appear about 7 days after infection.

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19
Q

What is crucial for the treatment of severely affected cats with FCV?

A

Intensive nursing care, supportive therapy, hydration, and ensuring food intake are crucial.

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20
Q

What are the common reasons for reduced food intake in FCV-affected cats?

A

Pyrexia, oral ulcers, and loss of sense of smell due to nasal congestion reduce food intake.

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21
Q

What can be used to treat fever and oral pain in cats with FCV?

A

Non-steroidal anti-inflammatory drugs can be used once the cat is rehydrated.

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22
Q

How can mucous nasal discharge in FCV-affected cats be treated?

A

Mucolytic drugs like bromhexine and nebulisation with saline can help combat nasal discharge.

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23
Q

What antiviral drug can be used to treat FCV?

A

Famciclovir can be used as an antiviral treatment for FCV.

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24
Q

Why might an oesophagostomy tube be used for FCV-affected cats?

A

It allows feeding and medication administration without touching the cat’s sore face, which is helpful when naso-oesophageal tubes are difficult to place.

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25
Q

What treatments are used for virulent systemic FCV disease?

A

Intensive supportive therapy, fluid therapy, antibiotics, steroids, and interferon are used, but mortality remains high.

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26
Q

What treatments are recommended for chronic stomatitis in FCV-infected cats?

A

Treatments include antibiotics, rigorous dental cleaning, corticosteroids, immunosuppressants, and in some cases, total teeth extraction.

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27
Q

Why is FCV a common problem in shelters?

A

FCV is common in shelters due to the risk of virus transmission, making virus control measures as important as vaccination.

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28
Q

How should cats be housed in shelters to limit FCV transmission?

A

Cats should be housed individually unless they come from the same household.

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29
Q

How long can FCV persist in the environment?

A

FCV can persist in the environment for about 1 month.

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30
Q

What disinfectants are effective against FCV?

A

Sodium hypochlorite (5% bleach diluted at 1:32), potassium peroxymonosulfate, chlorine dioxide, and other calicivirus-approved products.

31
Q

Why is FCV a frequent problem in breeding catteries?

A

FCV often affects young kittens as MDA wane, causing severe respiratory disease and sometimes death.

32
Q

Can vaccination of queens prevent FCV shedding?

A

No, vaccination won’t prevent virus shedding, but it may provide kittens with higher MDA levels for early protection.

33
Q

When should queens be vaccinated before breeding?

A

Queens should receive a booster vaccination before mating, but vaccination during pregnancy is discouraged.

34
Q

What type of vaccine should be used for pregnant queens, if vaccination is considered?

A

An inactivated vaccine should be used, as modified-live vaccines are not licensed for pregnant queens.

35
Q

What vaccination schedule is recommended for FCV in kittens?

A

Two injections at 9 and 12 weeks of age, a booster 1 year later, and then boosters every 3 years. In high-risk situations, a third vaccination at 16 weeks is recommended.

36
Q

Why are annual vaccinations sometimes recommended for cats in high-risk situations?

A

Cats in high-risk situations should be revaccinated annually to maintain protection.

37
Q

Why might cats that have recovered from FCV still be at risk of infection?

A

Recovered cats may not be protected for life, especially against distinct FCV strains not included in vaccines.

38
Q

What was the treatment provided to Cleo, the 8-year-old Burmese cat?

A

Cleo received fluids, an oesophagostomy tube, nutrition, cleaning of secretions, nebulisation, analgesia, ocular antibiotics, and antiviral (famciclovir) treatment.

39
Q

What disease is caused by Feline Herpesvirus (FHV)?

A

Feline viral rhinotracheitis, an upper respiratory tract disease.

40
Q

What is the typical outcome of an acute FHV infection?

A

Latent chronic infection, with cats becoming lifelong carriers of the virus.

41
Q

How is viral shedding in FHV carriers reactivated?

A

Reactivation occurs due to stress or immunosuppressant treatments, leading to shedding in oronasal and conjunctival secretions.

42
Q

How does FHV compare to FCV in terms of antigenic variation?

A

All FHV isolates are antigenically similar, making vaccination simpler compared to FCV, which has multiple strains.

43
Q

How long can FHV-infected cats shed the virus after infection?

A

Infected cats can shed the virus for up to 3 weeks.

44
Q

How is FHV transmitted between cats?

A

FHV transmission requires direct contact with a shedding cat, though fomites like bedding can also transmit the virus.

45
Q

How long can FHV survive in the environment?

A

FHV can survive for up to 48 hours in damp conditions.

46
Q

What are the primary disease signs of FHV infection?

A

Acute rhinitis, conjunctivitis, fever, depression, and anorexia.

47
Q

What eye condition is commonly associated with FHV infection?

A

FHV is associated with ulcerative, dendritic keratitis and may cause corneal ulcers and chronic sequestra.

48
Q

What is stromal keratitis, and how is it related to FHV?

A

Stromal keratitis is a secondary immune-mediated reaction caused by the presence of FHV in the epithelium or stroma.

49
Q

What chronic condition can result from damage to the nasal turbinates in FHV infection?

A

Chronic rhinitis can result from nasal turbinate damage during acute FHV infection.

50
Q

What dermatological condition may occur with FHV infection?

A

Dermatological disease is possible as a result of FHV infection.

51
Q

What samples can be tested for FHV diagnosis?

A

Conjunctival, corneal, or oropharyngeal swabs, corneal scrapings, or biopsies.

52
Q

What diagnostic methods are used for FHV?

A

PCR or virus isolation (VI).

53
Q

Why should caution be taken when interpreting positive PCR results for FHV?

A

Positive PCR results may reflect low-level shedding or viral latency, not necessarily active infection.

54
Q

How long do maternally derived antibodies (MDA) protect kittens from FHV?

A

MDA protects kittens during the first weeks of life, with antibody persisting for up to 10 weeks.

55
Q

Does natural FHV infection result in solid immunity?

A

No, natural infection protects against disease but not infection, and reinfection can occur.

56
Q

What is the recommended treatment for cats with severe FHV clinical signs?

A

Intravenous fluids to restore fluids, electrolytes, and acid-base balance, and ensuring food intake.

57
Q

What should be done if a cat with FHV stops eating due to loss of smell or oral ulcers?

A

Highly palatable food should be offered, possibly blended and warmed, and a feeding tube should be placed if intake is insufficient for 3 days.

58
Q

What is recommended to prevent secondary bacterial infections in cats with acute FHV?

A

Broad-spectrum antibiotics with good respiratory tract penetration.

59
Q

How can nasal discharge in FHV-infected cats be managed?

A

Wipe discharge with saline, apply a local ointment, and use mucolytic drugs like bromhexine or saline nebulisation.

60
Q

What is the role of famciclovir in the treatment of FHV?

A

Famciclovir is an antiviral drug effective in treating Herpes-related disease, including ocular and nasal symptoms.

61
Q

What should be used for ocular FHV, and what is a potential issue with treatment?

A

Topical ocular preparations can be used, though some antiviral drops may be irritant.

62
Q

Is FHV vaccination considered a core vaccination?

A

Yes, FHV vaccination is a core vaccination because the disease is common and can be fatal.

63
Q

What is the recommended quarantine period for new cats in shelters?

A

New cats should be quarantined for at least 2 weeks, preferably 3 weeks, to prevent infection spread.

64
Q

What management measures should be taken in shelters to prevent FHV outbreaks?

A

Shelter design should avoid cross-contamination, and new cats should be vaccinated as soon as possible.

65
Q

How does FHV commonly affect kittens in breeding catteries?

A

FHV typically affects kittens at 4-8 weeks of age as maternal antibodies (MDA) wane, often with the mother being the source due to reactivated latent infection.

66
Q

When should queens receive booster vaccinations for FHV?

A

Queens should receive booster vaccinations before mating to ensure kittens benefit from higher MDA levels.

67
Q

What is the earliest age for FHV vaccination in kittens?

A

FHV vaccines are licensed for use in kittens as early as 6 weeks, though vaccination at 4 weeks may be considered in some cases.

68
Q

What should be done if a queen consistently produces FHV-affected litters?

A

Early weaning should be considered, and the queen should not be bred again if she tests positive and consistently produces affected litters.

69
Q

How do FHV vaccines protect cats?

A

FHV vaccines induce both antibodies and cellular immunity, reducing virus excretion but not necessarily preventing infection.

70
Q

What is the recommended FHV vaccination schedule for kittens?

A

Kittens should be vaccinated at 9 weeks, followed by a second dose 2-4 weeks later, and an additional vaccination at 16 weeks to ensure MDA has waned.

71
Q

How often should booster vaccinations for FHV be given in low-risk cats?

A

For low-risk cats (e.g., indoor-only), booster vaccinations are recommended every 3 years.

72
Q

What is the recommendation for FHV booster vaccinations in high-risk cats?

A

High-risk cats (e.g., outdoor or visiting catteries) should receive annual booster vaccinations.

73
Q

How long does immunity against FHV typically last after vaccination?

A

Immunity against FHV lasts longer than 1 year in most vaccinated cats, according to experimental studies and serological data.

74
Q

Should recovered cats be vaccinated against FHV?

A

Yes, vaccination is recommended for recovered cats as they may still be susceptible to reinfection with other respiratory pathogens.